Latent and lytic Epstein‐Barr virus replication strategies
T Tsurumi, M Fujita, A Kudoh - Reviews in medical virology, 2005 - Wiley Online Library
Abstract The Epstein‐Barr virus (EBV) can choose between two alternative lifestyles; latent
or lytic replication. In the latent state, the EBV genomic DNA, which exists as a closed …
or lytic replication. In the latent state, the EBV genomic DNA, which exists as a closed …
Nonstructural proteins involved in genome packaging and replication of rotaviruses and other members of the Reoviridae
ZF Taraporewala, JT Patton - Virus research, 2004 - Elsevier
Rotaviruses, members of family Reoviridae, are a major cause of acute gastroenteritis of
infants and young children. The rotavirus genome consists of 11 segments of double …
infants and young children. The rotavirus genome consists of 11 segments of double …
Identification and characterization of the helix-destabilizing activity of rotavirus nonstructural protein NSP2
ZF Taraporewala, JT Patton - Journal of virology, 2001 - Am Soc Microbiol
The rotavirus nonstructural protein NSP2 self-assembles into homomultimers, binds single-
stranded RNA nonspecifically, possesses a Mg2+-dependent nucleoside triphosphatase …
stranded RNA nonspecifically, possesses a Mg2+-dependent nucleoside triphosphatase …
Initiation of Epstein-Barr virus lytic replication requires transcription and the formation of a stable RNA-DNA hybrid molecule at OriLyt
AJ Rennekamp, PM Lieberman - Journal of virology, 2011 - Am Soc Microbiol
The genetic elements of herpesvirus origins of lytic replication have been characterized in
detail; however, much remains to be elucidated concerning their functional role in replication …
detail; however, much remains to be elucidated concerning their functional role in replication …
Encyclopedia of EBV-encoded lytic genes: an update
T Murata - Human herpesviruses, 2018 - Springer
In addition to latent genes, lytic genes of EBV must also be of extreme significance since
propagation of the virus can be achieved only through execution of lytic cycle. Research on …
propagation of the virus can be achieved only through execution of lytic cycle. Research on …
Inhibition of S-phase cyclin-dependent kinase activity blocks expression of Epstein-Barr virus immediate-early and early genes, preventing viral lytic replication
A Kudoh, T Daikoku, Y Sugaya, H Isomura… - Journal of …, 2004 - Am Soc Microbiol
The induction of lytic replication of the Epstein-Barr virus (EBV) completely arrests cell cycle
progression, in spite of elevation of S-phase cyclin-dependent kinase (CDK) activity, thereby …
progression, in spite of elevation of S-phase cyclin-dependent kinase (CDK) activity, thereby …
Postreplicative mismatch repair factors are recruited to Epstein-Barr virus replication compartments
T Daikoku, A Kudoh, Y Sugaya, S Iwahori… - Journal of Biological …, 2006 - ASBMB
The mismatch repair (MMR) system, highly conserved throughout evolution, corrects
nucleotide mispairing that arise during cellular DNA replication. We report here that …
nucleotide mispairing that arise during cellular DNA replication. We report here that …
Nuclear transport of Epstein-Barr virus DNA polymerase is dependent on the BMRF1 polymerase processivity factor and molecular chaperone Hsp90
D Kawashima, T Kanda, T Murata, S Saito… - Journal of …, 2013 - Am Soc Microbiol
Epstein-Barr virus (EBV) replication proteins are transported into the nucleus to synthesize
viral genomes. We here report molecular mechanisms for nuclear transport of EBV DNA …
viral genomes. We here report molecular mechanisms for nuclear transport of EBV DNA …
Reovirus protein ςNS binds in multiple copies to single-stranded RNA and shares properties with single-stranded DNA binding proteins
AL Gillian, SC Schmechel, J Livny, LA Schiff… - Journal of …, 2000 - Am Soc Microbiol
Reovirus nonstructural protein ςNS interacts with reovirus plus-strand RNAs in infected cells,
but little is known about the nature of those interactions or their roles in viral replication. In …
but little is known about the nature of those interactions or their roles in viral replication. In …
The Epstein-Barr virus pol catalytic subunit physically interacts with the BBLF4-BSLF1-BBLF2/3 complex
K Fujii, N Yokoyama, T Kiyono, K Kuzushima… - Journal of …, 2000 - Am Soc Microbiol
ABSTRACT The Epstein-Barr virus (EBV)-encoded replication proteins that account for the
basic reactions at the replication fork are thought to be the EBV Pol holoenzyme, consisting …
basic reactions at the replication fork are thought to be the EBV Pol holoenzyme, consisting …