A key element of the European Union's Human Brain Project (HBP) and other large-scale
brain research projects is the simulation of large-scale model networks of neurons. Here, we …

A key goal in neuroscience is to explain how the operations of a neuron emerge from sets of
active channels with specific dendritic distributions. If general principles can be identified for …

The hippocampus is one of a group of remarkable structures embedded within the brain's
medial temporal lobe. Long known to be important for memory, it has been a prime focus of …

Taking a step-by-step approach to modelling neurons and neural circuitry, this textbook
teaches students how to use computational techniques to understand the nervous system at …

Why dopamine-containing neurons of the brain's substantia nigra pars compacta die in
Parkinson's disease has been an enduring mystery. Our studies suggest that the unusual …

The hippocampal theta rhythm plays important roles in information processing; however, the
mechanisms of its generation are not well understood. We developed a data-driven …

In the vast majority of brain areas, the firing rates of neurons, averaged over several hundred
milliseconds to several seconds, can be strongly modulated by, and provide accurate …

Principal medium spiny projection neurons (MSNs) of the striatum have long been thought to
be homogeneous in their somatodendritic morphology and physiology. Recent work using …

According to the temporal coding hypothesis, neurons encode information by the exact
timing of spikes. An example of temporal coding is the hippocampal phase precession …

Based on the authors' groundbreaking research, Automated EEG-Based Diagnosis of
Neurological Disorders: Inventing the Future of Neurology presents a research ideology, a …