Stem cells and liver regeneration

AW Duncan, C Dorrell, M Grompe - Gastroenterology, 2009 - Elsevier
One of the defining features of the liver is the capacity to maintain a constant size despite
injury. Although the precise molecular signals involved in the maintenance of liver size are …

CD38, a receptor with multifunctional activities: from modulatory functions on regulatory cell subsets and extracellular vesicles, to a target for therapeutic strategies

F Morandi, I Airoldi, D Marimpietri, C Bracci, AC Faini… - Cells, 2019 - mdpi.com
CD38 is a multifunctional cell surface protein endowed with receptor/enzymatic functions.
The protein is generally expressed at low/intermediate levels on hematological tissues and …

[PDF][PDF] Hepatic differentiation of amniotic epithelial cells

F Marongiu, R Gramignoli, K Dorko, T Miki… - …, 2011 - Wiley Online Library
Hepatocyte transplantation to treat liver disease is largely limited by the availability of useful
cells. Human amniotic epithelial cells (hAECs) from term placenta express surface markers …

Human amniotic epithelial stem cells: a promising seed cell for clinical applications

C Qiu, Z Ge, W Cui, L Yu, J Li - International journal of molecular sciences, 2020 - mdpi.com
Perinatal stem cells have been regarded as an attractive and available cell source for
medical research and clinical trials in recent years. Multiple stem cell types have been …

Amnion-derived stem cells: in quest of clinical applications

T Miki - Stem cell research & therapy, 2011 - Springer
In the promising field of regenerative medicine, human perinatal stem cells are of great
interest as potential stem cells with clinical applications. Perinatal stem cells could be …

Toward cell therapy using placenta-derived cells: disease mechanisms, cell biology, preclinical studies, and regulatory aspects at the round table

O Parolini, F Alviano, I Bergwerf, D Boraschi… - Stem cells and …, 2010 - liebertpub.com
Among the many cell types that may prove useful to regenerative medicine, mounting
evidence suggests that human term placenta-derived cells will join the list of significant …

The amniotic membrane: development and potential applications–a review

PO Favaron, RC Carvalho, J Borghesi… - … in domestic animals, 2015 - Wiley Online Library
Contents Foetal membranes are essential tissues for embryonic development, playing
important roles related to protection, breathing, nutrition and excretion. The amnion is the …

Transplantation of human amnion epithelial cells improves endometrial regeneration in rat model of intrauterine adhesions

X Ouyang, S You, Y Zhang, C Zhang… - Stem Cells and …, 2020 - liebertpub.com
Intrauterine adhesions (IUAs) are characterized by the injury of endometrium due to
curettage and/or endometritis. The loss of functional endometrium in uterine cavity usually …

Human amnion epithelial cells expressing HLA-G as novel cell-based treatment for liver disease

SC Strom, R Gramignoli - Human immunology, 2016 - Elsevier
Despite routine liver transplantation and supporting medical therapies, thousands of patients
currently wait for an organ and there is an unmet need for more refined and widely available …

Applications of amniotic membrane and fluid in stem cell biology and regenerative medicine

K Rennie, A Gruslin, M Hengstschläger… - Stem cells …, 2012 - Wiley Online Library
The amniotic membrane (AM) and amniotic fluid (AF) have a long history of use in surgical
and prenatal diagnostic applications, respectively. In addition, the discovery of cell …