Studies show that the autonomic nervous system (ANS) has an important impact on health in
general. In response to environmental demands, homeostatic processes are often …

Evidence suggests that the perioperative period and the excision of the primary tumour can
promote the development of metastases—the main cause of cancer-related mortality. This …

Purpose: Translational studies suggest that excess perioperative release of catecholamines
and prostaglandins may facilitate metastasis and reduce disease-free survival. This trial …

The influence of psychosocial factors on the development and progression of cancer has
been a longstanding hypothesis since ancient times. In fact, epidemiological and clinical …

Background Cancer surgery is necessary and life-saving. However, the majority of patients
develop postoperative recurrence and metastasis, which are the main causes of cancer …

Background: Surgical procedures, including primary tumor resection, have been suggested
to suppress immune competence and to promote postoperative infections and cancer …

Surgery for the removal of a primary tumor presents an opportunity to eradicate cancer or
arrest its progression, but is also believed to promote the outbreak of pre-existing …

Whereas evidence for the role of psychosocial factors in cancer initiation has been
equivocal, support continues to grow for links between psychological factors such as stress …

Background COX inhibitors and β-blockers were recently suggested to reduce cancer
progression through inhibition of tumor proliferation and growth factor secretion, induction of …

Surgery/anesthetic technique-stimulated immunosuppression in the perioperative period
might cause an increase in cancer-related mortality. Whether anesthetic technique can affect …