Growth-associated protein-43 (GAP-43) and brain acid-soluble protein 1 (BASP1) regulate
actin dynamics and presynaptic vesicle cycling at axon terminals, thereby facilitating axonal …

Protein S-acylation, the only fully reversible posttranslational lipid modification of proteins, is
emerging as a ubiquitous mechanism to control the properties and function of a diverse …

S-Nitrosylation is a redox-mediated posttranslational modification that regulates protein
function via covalent reaction of nitric oxide (NO)-related species with a cysteine thiol group …

Seattle, Washington 98195 Changeux—are better established for NO/O2. This hemoglobin-
based paradigm for protein regulation (JSS, Two signaling systems, based on the principle …

Protein post-translational modification by S-nitrosylation conveys a ubiquitous influence of
nitric oxide on signal transduction in eukaryotic cells. The wide functional purview of S …

Nitroglycerine has been used for over a century to treat coronary heart disease, and it has
long been suggested that humans synthesize oxides of nitrogen (Mitchell et al., 1916) …

NO was first characterized in the CNS as the intercellular messenger mediating the increase
in cyclic GMP levels that follows activation of glutamate receptors (Garthwaite et al., 1988) …

S-palmitoylation describes the reversible attachment of fatty acids (predominantly palmitate)
onto cysteine residues via a labile thioester bond. This posttranslational modification …

Nitric oxide (NO) is a signaling molecule that has capin the immune system in work by
DeGroote and Fang tured our imagination. According to the common view,(DeGroote et al …

Although maturing neurons undergo a precipitous decline in the expression of genes
associated with developmental axon growth, structural changes in axon arbors occur in the …