Coagulation factor VIIa enhances programmed death-ligand 1 expression and its stability in breast cancer cells to promote breast cancer immune evasion

S Paul, K Das, A Ghosh, A Chatterjee… - Journal of Thrombosis …, 2023 - Elsevier
Background Immunotherapy for breast cancer has not gained significant success.
Coagulation factor VIIa (FVIIa)-tissue factor (TF) mediated activation of protease-activated …

[HTML][HTML] Hypoxia-responsive gene F3 Promotes GBM Cell Proliferation and Migration through Activating NF-κB/p65 Signaling Pathway

A Yu, Y Wang, J Qin, J Lei, W Bao, Z Dong - Journal of Cancer, 2024 - pmc.ncbi.nlm.nih.gov
Background: Glioblastoma multiforme (GBM) is the most common malignant form of glioma,
but the molecular mechanisms underlying the progression of GBM in hypoxic …

Tissue factor pathway-related biomarkers in liver cancer: activated factor VII–antithrombin complex and tissue factor mRNA levels are associated with mortality

N Martinelli, S Moruzzi, S Udali, A Castagna… - Research and Practice …, 2024 - Elsevier
Background Tissue factor (TF), the main initiator of the coagulation cascade, plays a role in
cancer progression and prognosis. Activated factor VII–antithrombin complex (FVIIa-AT) is …

Bioinformatics analysis reveals link between alternative complement cascade pathway and colorectal cancer liver metastasis

CY Shi, Y Li, RQ Wei, J Deng, QL Zou, SQ Yang… - 2023 - researchsquare.com
Background Colorectal cancer (CRC) has a high incidence mortality rate and is
characterized by liver metastasis, which is the main cause of CRC patient death. In this …