Reactive oxygen species scavenging nanomedicine for the treatment of ischemic heart disease
Ischemic heart disease (IHD) is the leading cause of disability and mortality worldwide.
Reactive oxygen species (ROS) have been shown to play key roles in the progression of …
Reactive oxygen species (ROS) have been shown to play key roles in the progression of …
Doxorubicin-induced cardiotoxicity: an overview on pre-clinical therapeutic approaches
Doxorubicin is an effective chemotherapeutic agent prescribed to treat solid tumors (eg,
ovary, breast, and gastrointestinal cancers). This anti-cancer drug has various side effects …
ovary, breast, and gastrointestinal cancers). This anti-cancer drug has various side effects …
Molecular mechanism involved in cyclophosphamide-induced cardiotoxicity: Old drug with a new vision
Cyclophosphamide (CP) is an important anticancer drug which belongs to the class of
alkylating agent. Cyclophosphamide is mostly used in bone marrow transplantation …
alkylating agent. Cyclophosphamide is mostly used in bone marrow transplantation …
Reduction of doxorubicin-induced cardiotoxicity by Co-administration of smart liposomal doxorubicin and free quercetin: in vitro and in vivo studies
Doxorubicin is one of the most effective chemotherapeutic agents; however, it has various
side effects, such as cardiotoxicity. Therefore, novel methods are needed to reduce its …
side effects, such as cardiotoxicity. Therefore, novel methods are needed to reduce its …
Dexrazoxane ameliorates doxorubicin-induced cardiotoxicity by inhibiting both apoptosis and necroptosis in cardiomyocytes
X Yu, Y Ruan, X Huang, L Dou, M Lan, J Cui… - Biochemical and …, 2020 - Elsevier
Doxorubicin, as a first line chemotherapeutic agent, its usage is limited owing to
cardiotoxicity. Necroptosis is a new form of programmed cell death, and recent …
cardiotoxicity. Necroptosis is a new form of programmed cell death, and recent …
Acetylcholinesterase inhibitor ameliorates doxorubicin-induced cardiotoxicity through reducing RIP1-mediated necroptosis
T Khuanjing, B Ongnok, C Maneechote… - Pharmacological …, 2021 - Elsevier
Doxorubicin is an effective chemotherapeutic drug, but causes cardiotoxicity which limits its
use. Oxidative stress, mitochondrial dysfunction, and inflammation are closely implicated in …
use. Oxidative stress, mitochondrial dysfunction, and inflammation are closely implicated in …
Curcumin ameliorates doxorubicin-induced cardiotoxicity and hepatotoxicity via suppressing oxidative stress and modulating iNOS, NF-κB, and TNF-α in rats
G Ibrahim Fouad, KA Ahmed - Cardiovascular toxicology, 2022 - Springer
Doxorubicin (DOX) is one of the widely used anti-tumor drugs. However, DOX-induced
cardiotoxicity (DIC) and hepatotoxicity (DIH) are among the side effects that limited its …
cardiotoxicity (DIC) and hepatotoxicity (DIH) are among the side effects that limited its …
A foundational theoreticalAl12E12(E = N, P) adsorption and quinolone docking study: cage–quinolone pairs, optics and possible therapeutic and diagnostic …
Abstract This combined Al12 E 12 (E= N, P) surface adsorption and docking study describes
the new possibility of prospective potential probing (photophysical/optical) and therapy …
the new possibility of prospective potential probing (photophysical/optical) and therapy …
Liposomal resveratrol and/or carvedilol attenuate doxorubicin-induced cardiotoxicity by modulating inflammation, oxidative stress and S100A1 in rats
AM Alanazi, L Fadda, A Alhusaini, R Ahmad, IH Hasan… - Antioxidants, 2020 - mdpi.com
Doxorubicin (DOX) is a cytotoxic anthracycline antibiotic and one of the important
chemotherapeutic agents for different types of cancers. DOX treatment is associated with …
chemotherapeutic agents for different types of cancers. DOX treatment is associated with …
[HTML][HTML] Biometabolites of Tamarindus indica play a remarkable cardioprotective role as a functional food in doxorubicin-induced cardiotoxicity models
This research investigated the cardioprotective effects of Tamarindus indica extracts (TIEx)
in doxorubicin (Dox)-induced cardiotoxicity model. TIEx was tested for phytochemical and …
in doxorubicin (Dox)-induced cardiotoxicity model. TIEx was tested for phytochemical and …