Bone replacement might have been practiced for centuries with various materials of natural
origin, but had rarely met success until the late 19th century. Nowadays, many different bone …

The aim of this article was to synopsize platelet-rich plasma (PRP) use in musculoskeletal
pathologies through evidence-based assessment of the preparation, classification …

Objectives The use of platelet concentrates has gained increasing awareness in recent
years for regenerative procedures in modern dentistry. The aim of the present study was to …

Introduction Platelet-rich plasma (PRP) is nowadays widely applied in different clinical
scenarios, such as orthopedics, ophthalmology and healing therapies, as a growth factor …

The topical use of platelet concentrates is recent and its efficiency remains controversial.
Several techniques for platelet concentrates are available; however, their applications have …

Osteoarthritis (OA) is a common disease involving joint damage, an inadequate healing
response and progressive deterioration of the joint architecture. Autologous blood-derived …

Previous topical growth factor studies have shown that recombinant human platelet-derived
growth factor-BB isomer (rhPDGF-BB) is an efficacious treatment of chronic diabetic foot …

Platelet concentrates for surgical topical applications are nowadays often used, but
quantification of the long-term growth factor release from these preparations in most cases is …

Loss of articular cartilage through injury or disease presents major clinical challenges also
because cartilage has very poor regenerative capacity, giving rise to the development of …

Background: Numerous methods are available for platelet-rich plasma (PRP) generation,
but evidence defining the optimum composition is lacking. We hypothesized that leukocyte …