The direct (eg, radiation, microgravity) and indirect (eg, lifestyle perturbations) effects of
spaceflight extend across multiple systems resulting in whole-organism cardiovascular …

Neutron protein crystallography is a powerful tool for investigating protein chemistry
because it directly locates hydrogen atom positions in a protein structure. The visibility of …

The nonstructural protein 3 (NSP3) macrodomain of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2)(Mac1) removes adenosine diphosphate (ADP) ribosylation …

Proteins belong to the most complex colloidal system in terms of their physicochemical
properties, size and conformational-flexibility. This complexity contributes to their great …

Abstract The NASA mission Perfect Crystals used the microgravity environment on the
International Space Station (ISS) to grow crystals of human manganese superoxide …

A theory for the intermediate stage of crystal growth, where two defining equations one for
population continuity and another for mass-balance, is used to study the kinetics of the …

Metalloproteins catalyze a range of reactions, with enhanced chemical functionality due to
their metal cofactor. The reaction mechanisms of metalloproteins have been experimentally …

Neutron diffraction is one of the three crystallographic techniques (X-ray, neutron and
electron diffraction) used to determine the atomic structures of molecules. Its particular …

Biologically active vitamin B6-derivative pyridoxal 5′-phosphate (PLP) is an essential
cofactor in amino acid metabolic pathways. PLP-dependent enzymes catalyze a multitude of …

In this paper, we present a summary on how to obtain protein crystals from which better
diffraction images can be produced. In particular, we describe, in detail, quality evaluation of …