The present review is mainly focused upon the use of C-substituted oxazolidin-2-ones as
chiral auxiliaries in the stereocontrolled CC and CX (X= hetero atom) bond formation. The …

Lignin is a widely available second‐generation biopolymer and the main potential source of
renewable aromatic building blocks. Lignin‐based polyamines offer great potential in …

In our ongoing search for new bioactive fungal metabolites, four previously undescribed
oxazole carboxylic acid derivatives (1–4) for which we proposed the trivial names …

A concise and stereoselective total synthesis of (−)-salinosporamide A (1), a potent inhibitor
of the 20S proteasome that is in clinical development as an anticancer drug candidate, has …

A mild method is presented for the formation of N-acylated oxazolidinones that employs acid
fluorides and mild bases, such as i Pr2NEt and NEt3. Optimized reaction conditions for two …

In our ongoing search for new bioactive fungal metabolites, four previously undescribed
oxazole carboxylic acid derivatives (1–4) for which we proposed the trivial names …

Selective degradation of disease-causing proteins using proteolysis targeting chimeras
(PROTACs) has gained great attention, thanks to its several advantages over traditional …

A series of homo-and heterodimeric ligands containing κ agonist and μ agonist/antagonist
pharmacophores joined by a linker chain of varying lengths was synthesized and evaluated …

The first N-acylation of synthetically useful oxazolidinones with aldehydes using aerobic
oxidative NHC catalysis is reported. The reaction offers a broad scope of functionalized …

An indene-based thiazolidinethione chiral auxiliary was prepared in two steps from trans-1-
amino-2-indanol. Chlorotitanium enolates of this chiral auxiliary delivered excellent …