3d transition metals for C–H activation

P Gandeepan, T Müller, D Zell, G Cera… - Chemical …, 2018 - ACS Publications
C–H activation has surfaced as an increasingly powerful tool for molecular sciences, with
notable applications to material sciences, crop protection, drug discovery, and …

Bond-forming and-breaking reactions at sulfur (IV): sulfoxides, sulfonium salts, sulfur ylides, and sulfinate salts

D Kaiser, I Klose, R Oost, J Neuhaus… - Chemical …, 2019 - ACS Publications
Organosulfur compounds have long played a vital role in organic chemistry and in the
development of novel chemical structures and architectures. Prominent among these …

Electrochemical strategies for C–H functionalization and C–N bond formation

MD Kärkäs - Chemical Society Reviews, 2018 - pubs.rsc.org
Conventional methods for carrying out carbon–hydrogen functionalization and carbon–
nitrogen bond formation are typically conducted at elevated temperatures, and rely on …

Modern approaches for asymmetric construction of carbon–fluorine quaternary stereogenic centers: synthetic challenges and pharmaceutical needs

Y Zhu, J Han, J Wang, N Shibata, M Sodeoka… - Chemical …, 2018 - ACS Publications
New methods for preparation of tailor-made fluorine-containing compounds are in extremely
high demand in nearly every sector of chemical industry. The asymmetric construction of …

Radicals: reactive intermediates with translational potential

M Yan, JC Lo, JT Edwards… - Journal of the American …, 2016 - ACS Publications
This Perspective illustrates the defining characteristics of free radical chemistry, beginning
with its rich and storied history. Studies from our laboratory are discussed along with recent …

Approaches to obtaining fluorinated α-amino acids

J Moschner, V Stulberg, R Fernandes… - Chemical …, 2019 - ACS Publications
Fluorine does not belong to the pool of chemical elements that nature uses to build organic
matter. However, chemists have exploited the unique properties of fluorine and produced …

Fine design of photoredox systems for catalytic fluoromethylation of carbon–carbon multiple bonds

T Koike, M Akita - Accounts of Chemical Research, 2016 - ACS Publications
Conspectus Trifluoromethyl (CF3) and difluoromethyl (CF2H) groups are versatile structural
motifs, especially in the fields of pharmaceuticals and agrochemicals. Thus, the …

Main avenues in gold coordination chemistry

RP Herrera, MC Gimeno - Chemical Reviews, 2021 - ACS Publications
In this contribution, we provide an overview of the main avenues that have emerged in gold
coordination chemistry during the last years. The unique properties of gold have motivated …

Recent advances in catalyst-free photochemical reactions via electron-donor-acceptor (EDA) complex process

Y Yuan, S Majumder, M Yang, S Guo - Tetrahedron Letters, 2020 - Elsevier
This review summarizes the recent progress the emerging area of photochemical reaction
initiated by Electron-donor-acceptor (EDA) complex in synthetic organic chemistry. Recent …

Phosphorus-mediated sp2sp3 couplings for C–H fluoroalkylation of azines

X Zhang, KG Nottingham, C Patel, JV Alegre-Requena… - Nature, 2021 - nature.com
Fluoroalkyl groups profoundly affect the physical properties of pharmaceuticals and
influence almost all metrics associated with their pharmacokinetic and pharmacodynamic …