Retroviruses infect a broad range of vertebrate hosts that includes amphibians, reptiles, fish,
birds and mammals. In addition, a typical vertebrate genome contains thousands of loci …

Mammalian genomes have accumulated millions of retrotransposed sequences during
evolution. This material can be divided into long terminal repeat (LTR) retrotransposons that …

Whole-genome sequences are now available for many microbial species and clades,
however existing whole-genome alignment methods are limited in their ability to perform …

Bats possess extraordinary adaptations, including flight, echolocation, extreme longevity
and unique immunity. High-quality genomes are crucial for understanding the molecular …

Retroviral integration into germline DNA can result in the formation of a vertically inherited
proviral sequence called an endogenous retrovirus (ERV). Over the course of their …

Although extensive research has demonstrated host-retrovirus microevolutionary dynamics,
it has been difficult to gain a deeper understanding of the macroevolutionary patterns of host …

Viruses of the subfamily Orthoretrovirinae are defined by the ability to reverse transcribe an
RNA genome into DNA that integrates into the host cell genome during the intracellular virus …

Highlights•Retroviruses are a virus family of considerable medical and veterinary
importance.•Until recently, very little was known about deep retroviral origins.•New research …

Germline colonization by retroviruses results in the formation of endogenous retroviruses
(ERVs). Most colonization's occurred millions of years ago. However, in the Australo-Papuan …

Endogenous retroviruses comprise millions of discrete genetic loci distributed within the
genomes of extant vertebrates. These sequences, which are clearly related to exogenous …