Glucose homeostasis is tightly regulated to meet the energy requirements of the vital organs
and maintain an individual's health. The liver has a major role in the control of glucose …

Mitochondrial dysfunction is not only a hallmark of rare inherited mitochondrial disorders but
also implicated in age-related diseases, including those that affect the metabolic and …

Excess reactive oxygen species production and free radical formation can lead to oxidative
stress that can damage cells, tissues, and organs. Cellular oxidative stress is defined as the …

Liver plays a major role in maintaining glucose homeostasis in mammals. Under fasting
conditions, hepatic glucose production is critical as a source of fuel to maintain the basic …

The estrogen-related receptors (ERRs) comprise a small group of orphan nuclear receptor
transcription factors. The ERRα and ERRγ isoforms play a central role in the regulation of …

According to the World Health Organization (WHO) polycystic ovary syndrome (PCOS)
occurs in 4–8% of women worldwide. The prevalence of PCOS in Indian adolescents is …

As bisphenol A (BPA) has been shown to induce adverse effects on human health,
especially through the activation of endocrine pathways, it is about to be withdrawn from the …

One of the earliest maturation steps in cardiomyocytes (CMs) is the sarcomere protein
isoform switch between TNNI1 and TNNI3 (fetal and neonatal/adult troponin I). Here, we …

The retinoic acid receptor-related orphan receptor-α (RORα) is an important regulator of
various biological processes, including cerebellum development, circadian rhythm and …

The identification of the estrogen-related receptors (ERRs) as the first orphan nuclear
receptors ignited a new era in molecular endocrinology, which led to the discovery of new …