Advances in PET imaging of cancer

J Schwenck, D Sonanini, JM Cotton… - Nature Reviews …, 2023 - nature.com
Molecular imaging has experienced enormous advancements in the areas of imaging
technology, imaging probe and contrast development, and data quality, as well as machine …

Dynamic whole-body PET imaging: principles, potentials and applications

A Rahmim, MA Lodge, NA Karakatsanis… - European journal of …, 2019 - Springer
Purpose In this article, we discuss dynamic whole-body (DWB) positron emission
tomography (PET) as an imaging tool with significant clinical potential, in relation to …

Molecular imaging in drug development

JK Willmann, N Van Bruggen, LM Dinkelborg… - Nature reviews Drug …, 2008 - nature.com
Molecular imaging can allow the non-invasive assessment of biological and biochemical
processes in living subjects. Such technologies therefore have the potential to enhance our …

Molecular imaging–based dose painting: A novel paradigm for radiation therapy prescription

SM Bentzen, V Gregoire - Seminars in radiation oncology, 2011 - Elsevier
Dose painting is the prescription of a nonuniform radiation dose distribution to the target
volume based on functional or molecular images shown to indicate the local risk of relapse …

New approaches for imaging tumour responses to treatment

K Brindle - Nature Reviews Cancer, 2008 - nature.com
Tumour responses to treatment are still largely assessed from imaging measurements of
reductions in tumour size. However, this can take several weeks to become manifest and in …

Targeting the PI3K/AKT pathway for the treatment of prostate cancer

D Sarker, AHM Reid, TA Yap, JS De Bono - Clinical Cancer Research, 2009 - AACR
Despite recent advances in our understanding of the biological basis of prostate cancer, the
management of the disease, especially in the castration-resistant phase, remains a …

Clinical applications of PET in brain tumors

W Chen - Journal of nuclear medicine, 2007 - Soc Nuclear Med
Malignant gliomas and metastatic tumors are the most common brain tumors. Neuroimaging
plays a significant role clinically. In low-grade tumors, neuroimaging is needed to evaluate …

Theragnostic imaging for radiation oncology: dose-painting by numbers

SM Bentzen - The lancet oncology, 2005 - thelancet.com
Theragnostic imaging for radiation oncology is the use of molecular and functional imaging
to prescribe the distribution of radiation in four dimensions—the three dimensions of space …

PET/CT: Form and Function1

TM Blodgett, CC Meltzer, DW Townsend - Radiology, 2007 - pubs.rsna.org
Functional imaging with positron emission tomography (PET) is playing an increasingly
important role in the diagnosis and staging of malignant disease, image-guided therapy …

Imaging proliferation in brain tumors with 18F-FLT PET: comparison with 18F-FDG

W Chen, T Cloughesy, N Kamdar… - Journal of Nuclear …, 2005 - Soc Nuclear Med
3′-Deoxy-3′-18F-fluorothymidine (18F-FLT) is a recently developed PET tracer to image
tumor cell proliferation. We characterized 18F-FLT PET of brain gliomas and compared 18F …