Chemotherapy is a well-known and effective treatment for different cancers; unfortunately, it
has not been as efficient in the eradication of all cancer cells as been expected. The …

Doxorubicin is utilized for anti-neoplastic treatment for several decades. The utility of this
drug is limited due to its side effects. Generally, doxorubicin toxicity is originated from the …

Doxorubicin is an effective chemotherapeutic agent prescribed to treat solid tumors (eg,
ovary, breast, and gastrointestinal cancers). This anti-cancer drug has various side effects …

Doxorubicin (DOX) is the most widely used anthracycline anticancer agent; however, its
cardiotoxicity limits its clinical efficacy. Numerous studies have elucidated the mechanisms …

Perfluorooctanesulfonic acid (PFOS), a fluorine-containing organic compound, can be
widely detected in the environment and living organisms. Accumulating evidence has shown …

Cardiotoxicity is one of the main adverse effects of chemotheraphy, affecting the completion
of cancer therapies and the short-and long-term quality of life. Anthracyclines are currently …

Being a broad-spectrum anticancer drug, doxorubicin is indispensable for clinical treatment.
Unexpectedly, its cardiotoxic side effects have proven to be a formidable obstacle …

This study aimed to investigate the protective effects of long non-coding RNA KCNQ1OT1
against myocardial ischemia/reperfusion (I/R) injury following acute myocardial infarction, as …

Doxorubicin (DXR) is one of the most important chemotherapeutic agent. However,
nephrotoxicity reduces its clinical utility in humans. The aim of the study was to investigate …

Aims Doxorubicin is a prominent anticancer agent. However, its organotoxic potential has
restricted its clinical use. The current study was performed to investigate the protective effect …