Capping motifs in antimicrobial peptides and their relevance for improved biological activities

J Brango-Vanegas, ML Leite, MLR Macedo… - Frontiers in …, 2024 - frontiersin.org
N-capping (N-cap) and C-capping (C-cap) in biologically active peptides, including specific
amino acids or unconventional group motifs, have been shown to modulate activity against …

Metal coordination governs the antimicrobial efficacy of calcitermin derivatives

S Leveraro, K Garstka, P Śliwka, T Janek… - Dalton …, 2024 - pubs.rsc.org
Antimicrobial peptides are promising alternatives to classical antibiotics. Their microbicidal
activity can arise from different mechanisms, one of which is known as nutritional immunity …

Design, Synthesis and Antimicrobial Potential of Conjugated Metallopeptides Targeting DNA

MC Moreno-Ramirez, AS Arias-Bravo… - Scientia …, 2024 - mdpi.com
Antimicrobial resistance threatens the effective prevention and treatment of an increasingly
broad spectrum of infections caused by pathogenic microorganisms. This pressing …

His-Tagging: Exploring Precise Chemical Modification of Histidine-Containing Bioactive Peptide Sequences

S Chatterjee, B Paul, G Shanker - Synlett, 2024 - thieme-connect.com
The modification of biomolecules, particularly peptides, has garnered considerable attention
from researchers, effectively serving as a connection between chemistry and biology. The …