Recent developments in the synthesis and biological activity of acridine/acridone analogues
M Gensicka-Kowalewska, G Cholewiński… - RSC …, 2017 - pubs.rsc.org
Many people in the world struggle with cancer or bacterial, parasitic, viral, Alzheimer's and
other diseases. Therefore, many scientists seek new, more effective, more selective and less …
other diseases. Therefore, many scientists seek new, more effective, more selective and less …
[HTML][HTML] Acridine as an anti-tumour agent: a critical review
P Varakumar, K Rajagopal, B Aparna, K Raman… - Molecules, 2022 - mdpi.com
This review summarized the current breakthroughs in the chemistry of acridines as anti-
cancer agents, including new structural and biologically active acridine attributes. Acridine …
cancer agents, including new structural and biologically active acridine attributes. Acridine …
Artemisinin-derived hybrids and their anticancer activity
F Gao, Z Sun, F Kong, J Xiao - European journal of medicinal chemistry, 2020 - Elsevier
The emergence of drug-resistance and the low specificity of anticancer agents are the major
challenges in the treatment of cancer and can result in many side effects, creating an urgent …
challenges in the treatment of cancer and can result in many side effects, creating an urgent …
Combination therapy strategies for the treatment of malaria
S Alven, B Aderibigbe - Molecules, 2019 - mdpi.com
Malaria is a vector-and blood-borne infection that is responsible for a large number of
deaths around the world. Most of the currently used antimalarial therapeutics suffer from …
deaths around the world. Most of the currently used antimalarial therapeutics suffer from …
Medicinal chemistry of acridine and its analogues
P Prasher, M Sharma - MedChemComm, 2018 - pubs.rsc.org
'Acridine'along with its functional analogue 'Acridone'is the most privileged pharmacophore
in medicinal chemistry with diverse applications ranging from DNA intercalators …
in medicinal chemistry with diverse applications ranging from DNA intercalators …
Exploration of artemisinin derivatives and synthetic peroxides in antimalarial drug discovery research
Malaria is a life-threatening infectious disease caused by protozoal parasites belonging to
the genus Plasmodium. It caused an estimated 405,000 deaths and 228 million malaria …
the genus Plasmodium. It caused an estimated 405,000 deaths and 228 million malaria …
Synthesis of novel hybrids of thymoquinone and artemisinin with high activity and selectivity against colon cancer
T Fröhlich, B Ndreshkjana, JK Muenzner… - …, 2017 - Wiley Online Library
Colorectal cancer causes 0.5 million deaths each year. To combat this type of cancer the
development of new specific drug candidates is urgently needed. In the present work seven …
development of new specific drug candidates is urgently needed. In the present work seven …
Design of drug delivery systems containing artemisinin and its derivatives
BA Aderibigbe - Molecules, 2017 - mdpi.com
Artemisinin and its derivatives have been reported to be experimentally effective for the
treatment of highly aggressive cancers without developing drug resistance, they are useful …
treatment of highly aggressive cancers without developing drug resistance, they are useful …
Artemisinin and derivatives-based hybrid compounds: promising therapeutics for the treatment of cancer and malaria
S Peter, S Jama, S Alven, BA Aderibigbe - Molecules, 2021 - mdpi.com
Cancer and malaria are major health conditions around the world despite many strategies
and therapeutics available for their treatment. The most used strategy for the treatment of …
and therapeutics available for their treatment. The most used strategy for the treatment of …
Molecular hybridization as a strategy for developing artemisinin-derived anticancer candidates
E Marchesi, D Perrone, ML Navacchia - Pharmaceutics, 2023 - mdpi.com
Artemisinin is a natural compound extracted from Artemisia species belonging to the
Asteraceae family. Currently, artemisinin and its derivatives are considered among the most …
Asteraceae family. Currently, artemisinin and its derivatives are considered among the most …