Arene hydrogenation provides direct access to saturated carbo‐and heterocycles and thus
its strategic application may be used to shorten synthetic routes. This powerful …

At the advent of cross-coupling chemistry, carbon electrophiles based on halides or
pseudohalides were the only suitable electrophilic coupling partners. Almost two decades …

Chemists often use statistical analysis of reaction data with molecular descriptors to identify
structure-reactivity relationships, which can enable prediction and mechanistic …

We report here a new method for the synthesis of organohydrosilanes from phenols and
ketones. This method is established through reductive C− Si coupling of chlorohydrosilanes …

The formation of silicon–carbon bonds through the selective coupling of two strong
electrophilic bonds has been less developed. We report here silylation reactions that …

A nickel/zinc‐catalyzed cross‐electrophile coupling of alkyl electrophiles activated by an α‐
cyano group and chlorosilanes is reported. Elemental zinc is the stoichiometric reductant in …

Since C (sp3)–O bonds are a ubiquitous chemical motif in both natural and artificial organic
molecules, the universal transformation of C (sp3)–O bonds will be a key technology for …

A decarboxylative silylation of aliphatic N‐hydroxyphthalimide (NHPI) esters using Si− B
reagents as silicon pronucleophiles is reported. This C (sp3)− Si cross‐coupling is catalyzed …

Transition-metal catalyzed carbosilylation of alkenes using carbon electrophiles and
silylmetal (-B,-Zn) reagents as the nucleophiles offers a powerful strategy for synthesizing …

Cross-electrophile C–Si coupling has emerged as a promising tool for the construction of
organosilanes, but the potential of this method remains largely unexplored. Herein, we …