Transporter-guided delivery of nanoparticles to improve drug permeation across cellular barriers and drug exposure to selective cell types
Targeted nano-drug delivery systems conjugated with specific ligands to target selective cell-
surface receptors or transporters could enhance the efficacy of drug delivery and therapy …
surface receptors or transporters could enhance the efficacy of drug delivery and therapy …
The role of albumin receptors in regulation of albumin homeostasis: Implications for drug delivery
M Bern, KMK Sand, J Nilsen, I Sandlie… - Journal of Controlled …, 2015 - Elsevier
Albumin is the most abundant protein in blood and acts as a molecular taxi for a plethora of
small insoluble substances such as nutrients, hormones, metals and toxins. In addition, it …
small insoluble substances such as nutrients, hormones, metals and toxins. In addition, it …
Vitamin B12 functionalized layer by layer calcium phosphate nanoparticles: A mucoadhesive and pH responsive carrier for improved oral delivery of insulin
The present study investigates the potential of layer by layer coated calcium phosphate
nanoparticles–for oral delivery of insulin where Vitamin B12 grafted chitosan and sodium …
nanoparticles–for oral delivery of insulin where Vitamin B12 grafted chitosan and sodium …
Nanoparticle delivery systems with cell-specific targeting for pulmonary diseases
Respiratory disorders are among the most important medical problems threatening human
life. The conventional therapeutics for respiratory disorders are hindered by insufficient drug …
life. The conventional therapeutics for respiratory disorders are hindered by insufficient drug …
PEGylated nanomedicines: recent progress and remaining concerns
D Vllasaliu, R Fowler, S Stolnik - Expert opinion on drug delivery, 2014 - Taylor & Francis
Introduction: Recent biopharma deals related to nanocarrier drug delivery technologies
highlight the emergence of nanomedicine. This is perhaps an expected culmination of many …
highlight the emergence of nanomedicine. This is perhaps an expected culmination of many …
[HTML][HTML] Biotin receptor-mediated intracellular delivery of synthetic polypeptide-protein complexes
H Li, G Bruce, N Childerhouse, G Keegan… - Journal of Controlled …, 2023 - Elsevier
Pulmonary delivery offers a non-invasive route for the administration of biotherapeutics. In
this context, understanding and control of a transport into, and across cellular barriers is …
this context, understanding and control of a transport into, and across cellular barriers is …
Oral drug delivery of nanomedicine
Oral drug delivery is the most preferred administration route due to noninvasive, high patient
compliance, convenient to handle, and does not require any specific sterile conditions …
compliance, convenient to handle, and does not require any specific sterile conditions …
Recent advances in oral delivery of biologics: nanomedicine and physical modes of delivery
Introduction: Research into oral delivery of biologics has a long and rich history but has not
produced technologies used in the clinic. The area has evolved in terms of strategies to …
produced technologies used in the clinic. The area has evolved in terms of strategies to …
Formulation, characterization and in vitro anti-leishmanial evaluation of amphotericin B loaded solid lipid nanoparticles coated with vitamin B12-stearic acid conjugate
Despite the advancement of new anti-leishmanials, amphotericin B (AmB) prevails as one of
the most potent agent in the treatment of visceral leishmaniasis (VL), a neglected tropical …
the most potent agent in the treatment of visceral leishmaniasis (VL), a neglected tropical …
Transferrin functionization elevates transcytosis of nanogranules across epithelium by triggering polarity-associated transport flow and positive cellular feedback loop
D Yang, D Liu, H Deng, J Zhang, M Qin, L Yuan… - Acs Nano, 2019 - ACS Publications
Overcoming the epithelial barriers to enhance drug transport is a focused topic for
gastrointestinal, intratracheal, intranasal, vaginal, and intrauterine delivery. Nanomedicines …
gastrointestinal, intratracheal, intranasal, vaginal, and intrauterine delivery. Nanomedicines …