Neuroinflammation is a key pathophysiological mechanism implicated in the
neurodegenerative condition. One such condition implicating neuroinflammation is traumatic …

Preterm birth is associated with a high risk of morbidity and mortality including brain damage
and cerebral palsy. The development of brain injury in the preterm infant may be influenced …

Dimethyl sulfoxide (DMSO) is a polar organic solvent that is used to dissolve neuroprotective
or neurotoxic agents in neuroscience research. However, DMSO itself also has …

INTRODUCTION: Dimethyl sulfoxide is an amphiphilic compound whose miscibility with
water and its ability to dissolve lipophilic compounds make it an appreciated solvent in …

One of the main non-psychoactive phytocannabinoids of cannabis is cannabidiol (CBD),
which has attracted much attention for its neuroprotective roles. The present study was …

J. Neurochem.(2010) 113, 637–648. Abstract Traumatic brain injury is a devastating
neurological injury associated with significant morbidity and mortality. Medical therapies to …

Hypoxic-ischemic encephalopathy is the leading cause of permanent brain injury in term
newborns and currently has no cure. Inflammatory processes play a key role in the …

Sažetak Many biologic agents are weakly soluble in water. Therefore, they should be
dissolved in organic lipophilic solvents (vehicles). A drug vehicle is a substance of no …

Background Dimethyl sulfoxide (DMSO) is a widely used solvent and vehicle for in vivo and
in vitro administration of test compounds. Effects of DMSO independent of the test …

Excitotoxicity and imbalance of sodium and calcium homeostasis trigger pathophysiologic
processes in cerebral ischemia which can accelerate neuronal death. Neuroprotective role …