Severe traumatic brain injury (TBI) is currently managed in the intensive care unit with a
combined medical–surgical approach. Treatment aims to prevent additional brain damage …

A substantial minority of patients who survive an acquired brain injury develop a state of
sympathetic hyperactivity that can persist for weeks or months, consisting of periodic …

The brain controls the heart directly through the sympathetic and parasympathetic branches
of the autonomic nervous system, which consists of multi-synaptic pathways from myocardial …

A syndrome of paroxysmal, episodic sympathetic hyperactivity after acquired brain injury has
been recognized for almost 60 years. This project sought to simplify the confused …

Severe excessive autonomic overactivity occurs in a subgroup of people surviving acquired
brain injury, the majority of whom show paroxysmal sympathetic and motor overactivity …

A neurobiologically informed approach to a very difficult-to-treat disorder. This book
addresses one of the fundamental, understudied issues of borderline personality disorder …

Objective: To review evidence for the treatment of neuroleptic malignant syndrome (NMS)
and to discuss how to rechallenge patients with neuroleptics when continued …

Paroxysmal sympathetic hyperactivity (PSH) has predominantly been described after
traumatic brain injury (TBI), which is associated with hyperthermia, hypertension …

Severe traumatic brain injury (sTBI) is a major contributor to long-term disability and a
leading cause of death worldwide. Medical management of the sTBI patient, beginning with …

The management of Dysautonomia following severe traumatic brain injury (TBI) remains
problematic, primarily due to an inadequate understanding of the pathophysiology of the …