Mechanisms and regulation of alternative pre-mRNA splicing
Y Lee, DC Rio - Annual review of biochemistry, 2015 - annualreviews.org
Precursor messenger RNA (pre-mRNA) splicing is a critical step in the posttranscriptional
regulation of gene expression, providing significant expansion of the functional proteome of …
regulation of gene expression, providing significant expansion of the functional proteome of …
Nascent RNA analyses: tracking transcription and its regulation
The programmes that direct an organism's development and maintenance are encoded in its
genome. Decoding of this information begins with regulated transcription of genomic DNA …
genome. Decoding of this information begins with regulated transcription of genomic DNA …
Exon-intron circular RNAs regulate transcription in the nucleus
Z Li, C Huang, C Bao, L Chen, M Lin, X Wang… - Nature structural & …, 2015 - nature.com
Noncoding RNAs (ncRNAs) have numerous roles in development and disease, and one of
the prominent roles is to regulate gene expression. A vast number of circular RNAs …
the prominent roles is to regulate gene expression. A vast number of circular RNAs …
Coupling mRNA processing with transcription in time and space
DL Bentley - Nature Reviews Genetics, 2014 - nature.com
Maturation of mRNA precursors often occurs simultaneously with their synthesis by RNA
polymerase II (Pol II). The co-transcriptional nature of mRNA processing has permitted the …
polymerase II (Pol II). The co-transcriptional nature of mRNA processing has permitted the …
Alternative splicing: a pivotal step between eukaryotic transcription and translation
Alternative splicing was discovered simultaneously with splicing over three decades ago.
Since then, an enormous body of evidence has demonstrated the prevalence of alternative …
Since then, an enormous body of evidence has demonstrated the prevalence of alternative …
The roles of hnRNP A2/B1 in RNA biology and disease
Y Liu, SL Shi - Wiley Interdisciplinary Reviews: RNA, 2021 - Wiley Online Library
The RNA‐binding protein hnRNPA2/B1 is a member of the hnRNPs family and is widely
expressed in various tissues. hnRNPA2/B1 recognizes and binds specific RNA substrates …
expressed in various tissues. hnRNPA2/B1 recognizes and binds specific RNA substrates …
Regulation of alternative splicing through coupling with transcription and chromatin structure
Alternative precursor messenger RNA (pre-mRNA) splicing plays a pivotal role in the flow of
genetic information from DNA to proteins by expanding the coding capacity of genomes …
genetic information from DNA to proteins by expanding the coding capacity of genomes …
[HTML][HTML] SR proteins: binders, regulators, and connectors of RNA
S Jeong - Molecules and cells, 2017 - Elsevier
Serine and arginine-rich (SR) proteins are RNA-binding proteins (RBPs) known as
constitutive and alternative splicing regulators. As splicing is linked to transcriptional and …
constitutive and alternative splicing regulators. As splicing is linked to transcriptional and …
[HTML][HTML] Epigenetics in alternative pre-mRNA splicing
Alternative splicing plays critical roles in differentiation, development, and disease and is a
major source for protein diversity in higher eukaryotes. Analysis of alternative splicing …
major source for protein diversity in higher eukaryotes. Analysis of alternative splicing …
Alternative splicing and protein diversity: plants versus animals
S Chaudhary, W Khokhar, I Jabre, ASN Reddy… - Frontiers in plant …, 2019 - frontiersin.org
Plants, unlike animals, exhibit a very high degree of plasticity in their growth and
development and employ diverse strategies to cope with the variations during diurnal cycles …
development and employ diverse strategies to cope with the variations during diurnal cycles …