The endothelium can evoke relaxations of the underlying vascular smooth muscle, by
releasing vasodilator substances. The best‐characterized endothelium‐derived relaxing …

Vascular endothelium has important regulatory functions in the cardiovascular system and a
pivotal role in the maintenance of vascular health and metabolic homeostasis. It has long …

Photoplethysmography (PPG) is a widely available non-invasive optical technique to
visualize pressure pulse waves (PWs). Pulse transit time (PTT) is a physiological parameter …

Cushing syndrome (CS), characterised by endogenous or exogenous glucocorticoid
hormone excess, is associated with several systemic complications, including impaired …

Objectives: Patients with overt and subclinical Cushing's syndrome frequently develop
hypertension, metabolism disorders, and atherosclerotic lesions. The aim of the present …

The causes of adrenal Cushing's syndrome (CS) encompass a wide spectrum of adrenal
cortisol proliferations that exhibit clinical and molecular heterogeneity. The aims of our study …

Obesity is prevalent worldwide and associated with co-morbidities that result in increased
cardiovascular risk. Hypertension is the most prevalent obesity comorbidity associated with …

Long-standing exposure to endogenous cortisol excess is associated with high
cardiovascular risk. The aim of our study was to investigate arterial stiffness, which has been …

Context: In active Cushing's syndrome (CS), patients suffer from endothelial dysfunction and
premature atherosclerosis. However, it is uncertain to what extent vascular health recovers …

Abstract Background/Aims: Endogenous Cushing's syndrome is associated with a higher
risk of cardiovascular morbidity and mortality. Previous literature suggested multiple …