Malaria remains a significant threat to global health, and despite concerted efforts to curb the
disease, malaria-related morbidity and mortality increased in recent years. Malaria is caused …

Apicomplexan parasites are a group of eukaryotic protozoans with diverse biology that have
affected human health like no other group of parasites. These obligate intracellular parasites …

Apicomplexan parasites have immense impacts on humanity, but their basic cellular
processes are often poorly understood. Where endocytosis occurs in these cells, how …

Malaria is caused by infection of the erythrocytes by the parasites Plasmodium. Inside the
erythrocytes, the parasites multiply via schizogony, an unconventional cell division mode …

Taxon-specific proteins are key determinants defining the biology of all organisms and
represent prime drug targets in pathogens. However, lacking comparability with proteins in …

Single amino acid changes in the parasite protein Kelch13 (K13) result in reduced
susceptibility of P. falciparum parasites to artemisinin and its derivatives (ART). Recent work …

Twenty years since the publication of the Plasmodium falciparum and P. berghei genomes
one-third of their protein-coding genes still lack functional annotation. In the absence of …

In the last 10 years, proximity‐dependent biotinylation (PDB) techniques greatly expanded
the ability to study protein environments in the living cell that range from specific protein …

Abstract In Bandiagara, Mali, children experience on average two clinical malaria episodes
per year. However, even in the same transmission area, the number of uncomplicated …

Mature gametocytes of Plasmodium falciparum display a banana (falciform) shape conferred
by a complex array of subpellicular microtubules (SPMT) associated with the inner …