Long-term changes in synaptic transmission between neurons in the brain are considered
the cellular basis of learning and memory. Over the last few decades, many studies have …

A link between obesity and cerebral health is receiving growing recognition. Here, we
investigate in the frontal cortex and hippocampus the potential involvement of cholinergic …

The oligomeric form of the peptide amyloid beta 42 (Abeta42) contributes to the
development of synaptic abnormalities and cognitive impairments associated with …

Mutations of SCN1A, which encodes the voltage-gated sodium channel Nav1. 1, can cause
epilepsy disorders such as Dravet syndrome (DS) that are comorbid with wide-ranging …

Parvalbumin-positive basket cells (PV BCs) of the CA1 hippocampus are active participants
in theta (5–12 Hz) and gamma (20–80 Hz) oscillations in vivo. When PV BCs are driven at …

Glyphosate (Gly) is a broad-spectrum herbicide responsible for the inhibition of the enzyme
5-enolpyruvylshikimate-3-phosphate synthase known to be expressed exclusively in plants …

At fast-transmitting presynaptic terminals Ca2+ enter through voltage gated calcium
channels (CaVs) and bind to a synaptic vesicle (SV)-associated calcium sensor (SV-sensor) …

In this paper we use a simple model of presynaptic neuromodulation of GABA signaling to
decipher paired whole-cell recordings of frequency dependent cholinergic neuromodulation …

The cholinergic system plays an essential role in central respiratory control, but the
underlying mechanisms remain elusive. We used whole-cell recordings in brainstem slices …

The brain contains a large number of neurons, each of which typically has thousands of
synaptic connections. Its functionality, whether function or dysfunction, depends on the …