Exposure to particulate matter (PM) like nanoparticles (NPs) has increased in the last
century due to increased combustion processes, road traffic, etc. In addition, the progress in …

Abstract This EAACI Task Force document aims at providing the readers with a
comprehensive and complete overview of the currently available tools for diagnosis of nasal …

Background Exposure to fine and ultra-fine ambient particles is still a problem of concern in
many industrialised parts of the world and the intensified use of nanotechnology may further …

The purpose of this study was to investigate the human nasal epithelial cell line RPMI 2650
regarding its usefulness as in vitro model for drug permeation studies. Particularly, the …

The nasal route is widely used for the administration of drugs for both topical and systemic
action. At an early stage in drug discovery and during the development process, it is …

Recent studies indicate that inhaled ultrafine particles can pass into the circulation. To study
this translocation in an in vitro model three types of pulmonary epithelial cells were …

During the development of intranasal drug delivery systems for local/systemic effect or brain
targeting, it is necessary to assess its cytotoxicity and drug transport through nasal …

The nasal route is commonly used for local delivery of drugs to treat inflammatory conditions.
It is also an attractive route for systemic delivery of some drugs. Irrespective of intended use …

For establishing a precise system for predicting in vivo bioavailability following intranasal
(IN) administration, the relationships among membrane permeability of drugs across Calu-3 …

This study tests the hypothesis that human nasal RPMI 2650 cells grown at an air–liquid
interface is a feasible model for drug transport studies via the nasal route. RPMI 2650 cells …