An estimated 20–25% of the population is affected by chronic, non-communicable
inflammatory skin diseases. Chronic skin inflammation has many causes. Among the most …

Chronic spontaneous urticaria (CSU) is a mast cell–driven skin disease characterized by the
recurrence of transient wheals, angioedema, or both for more than 6 weeks. Autoimmunity is …

Pemphigoid diseases are a group of well defined autoimmune disorders that are
characterised by autoantibodies against structural proteins of the dermal–epidermal junction …

Pemphigus and bullous pemphigoid are autoantibody-mediated blistering skin diseases. In
pemphigus, keratinocytes in epidermis and mucous membranes lose cell-cell adhesion, and …

Bullous pemphigoid (BP) is a major autoimmune blistering skin disorder, in which a majority
of the autoantibodies (autoAbs) target the juxtamembranous extracellular noncollagenous …

There are several lines of evidence indicating that the physiopathological bases of bullous
pemphigoid (BP), the most common subepidermal autoimmune bullous disease, are …

Patients with chronic spontaneous urticaria (CSU) are widely held to often have other
autoimmune disorders, including autoimmune thyroid disease. Here, we systematically …

Bullous pemphigoid (BP) is the most common autoimmune bullous disorder which is
characterized by autoantibodies against hemidesmosomal proteins of the skin and mucous …

Mast cells are multifunctional cells that initiate not only IgE-dependent allergic diseases but
also play a fundamental role in innate and adaptive immune responses to microbial …

Importance Bullous pemphigoid (BP) is by far the most frequent autoimmune blistering
disease. The presence of IgE autoantibodies against the transmembrane protein BP antigen …