Vibrio spp. are highly motile Gram-negative bacteria, ubiquitously found in aquatic
environments. Some Vibrio s are responsible for disease and morbidity of marine …

Cholera: recent updates : Current Opinion in Infectious Diseases Cholera: recent updates :
Current Opinion in Infectious Diseases Log in or Register Subscribe to journalSubscribe Get …

Vibrio cholerae, a noninvasive mucosal pathogen, is endemic in more than 50 countries.
Oral cholera vaccines, based on killed whole-cell strains of Vibrio cholerae, can provide …

We tested an oral enterotoxigenic Escherichia coli (ETEC) vaccine, ETVAX, consisting of
inactivated E. coli overexpressing the most prevalent ETEC colonization factors (CFs) and a …

The mechanism of protection against cholera afforded by previous illness or vaccination is
currently unknown. We have recently shown that antibodies targeting O-specific …

Summary Background In October, 2017, WHO launched a strategy to eliminate cholera by
2030. A primary challenge in meeting this goal is the limited global supply capacity of oral …

Estimates of incidence based on medically attended cholera can be severely biased. Vibrio
cholerae O1 leaves a lasting antibody signal and recent advances showed that these can be …

Na+/H+ exchangers (NHEs) are expressed in virtually all human tissues and organs. Two
major tasks of those NHE isoforms that are located in plasma membranes are cell volume …

Oral cholera vaccines (OCVs) are being increasingly employed, but current killed
formulations generally require multiple doses and lack efficacy in young children. We …

There is a need to develop cholera vaccines that are protective in young children under 5
years of age, which induce long-term immunity, and which can be incorporated into the …