Myopia is far beyond its inconvenience and represents a true, highly prevalent, sight-
threatening ocular condition, especially in Asia. Without adequate interventions, the current …

Purpose Despite extensive research, mechanisms regulating postnatal eye growth and
those responsible for ametropias are poorly understood. With the marked recent increases …

Myopia is a dynamic and rapidly moving field, with ongoing research providing a better
understanding of the etiology leading to novel myopia control strategies. In 2019, the …

The opsin family of G-protein-coupled receptors are used as light detectors in animals.
Opsin 5 (also known as neuropsin or OPN5) is a highly conserved opsin that is sensitive to …

Rhodopsins are photoreceptive membrane proteins consisting of a common heptahelical
transmembrane architecture that contains a retinal chromophore. Rhodopsin was first …

Ultraviolet (UV) light occupies the spectral range of wavelengths slightly shorter than those
visible to humans. Because of its shorter wavelength, it is more energetic (and potentially …

Myopia has become a major public health concern, particularly across much of Asia. It has
been shown in multiple studies that outdoor activity has a protective effect on myopia …

Gq proteins are universally important for signal transduction in mammalian cells. The
underlying kinetics and transformation from extracellular stimuli into intracellular signaling …

We live on a planet that is bathed in daily and seasonal sunlight cycles. In this context,
terrestrial life forms have evolved mechanisms that directly harness light energy (plants) or …

Zebrafish represent the one alternative vertebrate, genetic model system to mice that can be
easily manipulated in a laboratory setting. With the teleost Medaka (Oryzias latipes), which …