Diabetic wound infection is a common disease that has significantly reduced people's
quality of life. Although tremendous achievements have been made in clinical treatment, the …

Reactive oxygen species (ROS) are deadly weapons used by phagocytes and other cell
types, such as lung epithelial cells, against pathogens. ROS can kill pathogens directly by …

Increased oxidative burden contributes to the pathogenesis of most inflammatory diseases
and is associated with aging and chronic inflammation. Macrophages contribute to the …

Neutrophils play a critical role in cancer, with both protumor and antitumor neutrophil
subpopulations reported. The antitumor neutrophil subpopulation has the capacity to kill …

Chagas disease caused by Trypanosoma cruzi remains an important neglected tropical
disease and a cause of significant morbidity and mortality. No longer confined to endemic …

Current knowledge of the biochemistry of Trypanosoma cruzi has led to the development of
new drugs and the understanding of their mode of action. Some trypanocidal drugs such as …

Oxidative damage contributes to microbe elimination during macrophage respiratory burst.
Nuclear factor, erythroid-derived 2, like 2 (NRF2) orchestrates antioxidant defenses …

The excessive production of reactive oxidative species (ROS) associated with inflammation
leads to a condition of oxidative stress. Cyclooxygenase-2 (COX-2), PGE 2, and matrix …

There is growing evidence to suggest that chagasic myocardia are exposed to sustained
oxidative stress induced injuries that may contribute to disease progression. Trypanosoma …

Background During Trypanosoma cruzi infection, macrophages produce reactive oxygen
species (ROS) in a process called respiratory burst. Several works have aimed to elucidate …