Acidity is one of the main characteristics of OSCC (oral squamous cell carcinoma) as a solid
tumor. The V-ATPase is the primary regulator of the tumor microenvironment, by means of …

Adenosine triphosphate, ATP, is the energy currency of living cells. While ATP synthases of
archae and ATP synthases of pro‐and eukaryotic organisms operate as energy producers …

The ability of subunit C of eukaryotic V-ATPases to bind ADP and ATP is demonstrated by
photoaffinity labeling and fluorescence correlation spectroscopy (FCS). Quantitation of the …

Vacuolar ATPases (V-ATPases) are present in specialized proton secretory cells in which
they pump protons across the membranes of various intracellular organelles and across the …

Vacuolar ATPases use the energy derived from ATP hydrolysis, catalyzed in the A3B3 sector
of the V1 ATPase to pump protons via the membrane-embedded VO sector. The energy …

Subunit E of the vacuolar ATPase (V-ATPase) contains an N-terminal extended α helix
(Rishikesan et al. J Bioenerg Biomembr 43: 187–193, 2011) and a globular C-terminal part …

V-ATPases (vacuolar ATPases) are responsible for acidification of intracellular
compartments and, in certain cases, proton transport across the plasma membrane of …

During the last decades impressive progress has been made in understanding of the
catalytic mechanism of F-type ATP synthase, which is the key enzyme in the energy …

Introducción El carcinoma oral de células escamosas (COCE), representa el 95% de las
lesiones malignas de la cavidad oral. La biopsia es la prueba definitiva para el diagnóstico …

Abstract The vacuolar (H+)-ATPases (V-ATPases) are ATP-driven proton pumps composed
of a peripheral V 1 domain and a membrane embedded V 0 domain. Regulated assembly of …