Directed evolution aims to expedite the natural evolution process of biological molecules
and systems in a test tube through iterative rounds of gene diversifications and library …

Metabolomics is one omics approach that can be used to acquire comprehensive
information on the composition of a metabolite pool to provide a functional screen of the …

Metabolic heterogeneity of cancer contributes significantly to its poor treatment outcomes
and prognosis. As a result, studies continue to focus on identifying new biomarkers and …

Native mass spectrometry (nMS) is evolving into a workhorse for structural biology. The
plethora of online and offline preparation, separation, and purification methods as well as …

Metabolomics is now considered a wide-ranging, sensitive and practical approach to
acquire useful information on the composition of a metabolite pool present in any organism …

Proteomes are complex—much more so than genomes or transcriptomes. Thus, simplifying
their analysis does not simplify the issue. Proteomes are of proteoforms, not canonical …

The chemical differences between individual cells within large cellular populations provide
unique information on organisms' homeostasis and the development of diseased states …

A new strategy has been developed for characterization of the most challenging complex
mixtures to date, using a combination of custom-designed experiments and a new data pre …

Paleontology, archeology, and art history provide crucial information for the understanding
of human evolution throughout ages and its habits. Past animal and plant species are also …

We describe a mass spectrometry (MS) analytical platform resulting from the novel
integration of acoustic droplet ejection (ADE) technology, an open-port interface (OPI), and …