Treatments and outcomes in high‐risk gestational trophoblastic neoplasia: A systematic review and meta‐analysis

BB Albright, T Ellett, HE Knochenhauer… - … Journal of Obstetrics …, 2023 - Wiley Online Library
Background High‐risk gestational trophoblastic neoplasia (GTN) is rare and treated with
diverse approaches. Limited published institutional data has yet to be systematically …

Gestational trophoblastic neoplasia lethality among Brazilian women: a retrospective national cohort study

F Freitas, A Braga, M Viggiano, LGC Velarde… - Gynecologic …, 2020 - Elsevier
Objective To investigate GTN lethality among Brazilian women comparing cases of death by
GTN with those who survived, thereby identifying factors associated with GTN lethality …

Direct comparisons of efficacy and safety between actinomycin-D and methotrexate in women with low-risk gestational trophoblastic neoplasia: a meta-analysis of …

J Hao, W Zhou, M Zhang, H Yu, T Zhang, R An, Y Xue - BMC cancer, 2021 - Springer
Abstract Background Actinomycin-D (Act-D) and Methotrexate (MTX) are both effective first-
line agents for low-risk gestational trophoblastic neoplasia (LRGTN) with no consensus …

Clinical significance of circulating tumor cells in predicting disease progression and chemotherapy resistance in patients with gestational choriocarcinoma

W He, M Hou, H Zhang, C Zeng, S He… - … journal of cancer, 2019 - Wiley Online Library
Gestational choriocarcinoma (GC) is a highly aggressive tumor. In our study, we
systematically investigated EpCAM/CD147 expression characteristics in patients with GC …

Pulse actinomycin D as first-line treatment of low-risk post-molar non-choriocarcinoma gestational trophoblastic neoplasia

L Li, X Wan, F Feng, T Ren, J Yang, J Zhao, F Jiang… - BMC cancer, 2018 - Springer
Background Little data exists predicting the resistance to actinomycin D (Act-D) single-agent
for gestational trophoblastic neoplasia (GTN). The objective was to determine the overall …

[HTML][HTML] The 16-year experience in treating low-risk gestational trophoblastic neoplasia patients with failed primary methotrexate chemotherapy

X Wu, J Qin, T Shen, W Fei, L Chen… - Journal of Gynecologic …, 2020 - ncbi.nlm.nih.gov
Objective To assess the outcomes and toxic effects of 5-day actinomycin D (Act-D) salvage
therapy and to explore the predictors of Act-D resistance in patients with low-risk gestational …

Case report: first-line immune checkpoint inhibitor plus chemotherapy for oral metastasis in a patient with ultra high-risk gestational choriocarcinoma

Y Chen, H Ye, J Tang, Y Weng, J Zhang… - Cancer Management …, 2022 - Taylor & Francis
Choriocarcinoma (CC) tends to metastasize early into various organs and may exhibit
peculiar clinical behaviors specific to metastases. Although chemotherapy has …

Gestational trophoblastic neoplasia: experience at Salah Azaiez Institute

R Batti, A Mokrani, H Rachdi, H Raies… - Pan African Medical …, 2019 - ajol.info
Case series Page 1 Page number not for citation purposes 1 Gestational trophoblastic neoplasia:
experience at Salah Azaiez Institute Rim Batti1,&, Amina Mokrani1,, Haifa Rachdi1, Henda …

Clinical characteristics of gestational trophoblastic neoplasia: a 15-year hospital-based study

R Sun, Y Zhang, W Zheng, Q Tian, R An… - International Journal of …, 2016 - ijgc.bmj.com
Objective To analyze the clinical profile of invasive mole (IM) and choriocarcinoma (CCA) in
the past 15 years in Western China. Materials and Methods A retrospective study was …

Role of emergency surgery for fatal complications of gestational trophoblastic neoplasia: a single-center experience

Z Wang, P Han, X Zhu, J Ying, J Qian - Cancer Management and …, 2022 - Taylor & Francis
Purpose High-risk gestational trophoblastic neoplasia (GTN) can lead to fatal complications;
however, few reports have assessed emergency surgery as a treatment option for such …