Pyrazole and its derivatives are considered a pharmacologically important active scaffold
that possesses almost all types of pharmacological activities. The presence of this nucleus in …

Opuntia dillenii (Ker Gawl.) Haw. belongs to the Cactaceae family and is native to the arid
and semi‐arid regions of Mexico and the southern United States. O. dillenii are now used as …

Pyrazole derivatives have their own importance in aromatic organic heterocycle family.
Application of these derivatives in chemistry and biology has attracted increasing interest …

A series of synthesized compounds based on pyrazole and imidazole skeletons prepared by
palladium catalysts via a one-pot reaction was screened to determine their inhibitory …

Background. Nigella sativa L.(NS) is an aromatic and medicinal plant commonly used in
Mediterranean cuisine. Its grains contain a large amount of fixed oil and have many …

Inspired by the wide application of amides in plant pathogens, a series of novel 1-substituted-
5-trifluoromethyl‑1H‑pyrazole-4-carboxamide derivatives were designed and synthesized …

Mast cells are unique immune cells that function as sentinels in host defence reactions,
including immediate hypersensitivity responses and allergic responses. The mast cell …

The present work describes design of a small library of new 1, 2, 3-triazole-appended bis-
pyrazoles by using a molecular hybridization approach, and the synthesized hybrids were …

Herein, new substituted ligands based on pyrazole (L1–L4) were synthesized via a one-step
by condensing (1 H-pyrazole-1-yl) methanol with different primary amine compounds. The …

The objective of our work is the preparation of the new catalysts for catecholase, whose
principle is based on the catechol oxidation reaction which presents a major challenge in …