The Gelatinase Inhibitor ACT-03 Reduces Gliosis in the Rapid Kindling Rat Model of Epilepsy, and Attenuates Inflammation and Loss of Barrier Integrity In Vitro

DWM Broekaart, TS Zimmer, ST Cohen, R Tessers… - Biomedicines, 2022 - mdpi.com
Matrix metalloproteinases (MMPs) are endopeptidases responsible for the cleavage of intra-
and extracellular proteins. Several brain MMPs have been implicated in neurological …