Inflammaging and frailty in immune-mediated rheumatic diseases: how to address and score the issue

F Salaffi, A Di Matteo, S Farah, M Di Carlo - Clinical Reviews in Allergy & …, 2023 - Springer
Frailty is a new concept in rheumatology that can help identify people more likely to have
less favorable outcomes. Sarcopenia and inflammaging can be regarded as the biological …

Frailty in rheumatic diseases

F Motta, A Sica, C Selmi - Frontiers in immunology, 2020 - frontiersin.org
Frailty is a syndrome characterized by the decline in the physiologic reserve and function of
several systems, leading to increased vulnerability and adverse health outcomes. While …

Frailty in inflammatory bowel diseases: an emerging concept

B Kochar, AR Orkaby… - Therapeutic …, 2021 - journals.sagepub.com
Inflammatory bowel diseases (IBD), consisting of Crohn's disease and ulcerative colitis, are
chronic remitting, relapsing inflammatory conditions of the gastrointestinal tract. While …

Frailty in rheumatoid arthritis: A systematic review and meta-analysis

RC Gao, ZG Wu, ZZ Wu, M Hao, GC Wu - Joint Bone Spine, 2022 - Elsevier
Objective Rheumatoid arthritis (RA) may cause damage to multiple organs and may further
restrict the patient's physical, psychological and social functions. This meta-analysis aimed …

Frailty and rheumatic diseases: evidence to date and lessons learned

SB Lieber, KD Wysham, SE Sattui, R Yung… - The Lancet …, 2024 - thelancet.com
Frailty represents a dynamic multisystem state of reduced physiological reserve that
increases vulnerability to adverse health outcomes. Frailty occurs prematurely in adults with …

Frailty in rheumatoid arthritis and its relationship with disease activity, hospitalisation and mortality: a longitudinal analysis of the Scottish Early Rheumatoid Arthritis …

P Hanlon, F Morton, S Siebert, BD Jani, BI Nicholl… - RMD open, 2022 - rmdopen.bmj.com
Objective To assess the prevalence of frailty in rheumatoid arthritis (RA) and its association
with baseline and longitudinal disease activity, all-cause mortality and hospitalisation …

Frailty prevalence according to the Survey of Health, Ageing and Retirement in Europe-Frailty Instrument (SHARE-FI) definition, and its variables associated, in …

F Salaffi, M Di Carlo, M Carotti, S Farah… - Aging Clinical and …, 2021 - Springer
Background Frailty is a frequent condition in patients with knee osteoarthritis (KOA).
However, there are different constructs on how to define it. Survey of Health, Ageing and …

[PDF][PDF] Prevalence of frailty and pre-frailty in patients with rheumatoid arthritis: a systematic literature review and meta-analysis

S Germonpré, S Mulier, L Falzon, A Boonen… - Clin Exp …, 2022 - clinexprheumatol.org
Objective Frailty is a common geriatric syndrome and is characterised by a decreased
physiological reserve and increased vulnerability to stressors. Pre-frailty is a risk-state …

Frailty in relation to psycho‐social factors in elderly patients with rheumatoid arthritis: a cross‐sectional mixed qualitative‐quantitative study

F Cleutjens, A van Moerbeke, A Boonen… - International Journal …, 2021 - Wiley Online Library
Aim The aim of the study was to explore in patients with rheumatoid arthritis (RA)≥ 55
years:(1) whether the occurrence of frailty as measured by the Groningen Frailty Indicator …

Frailty in people with rheumatoid arthritis: a systematic review of observational studies

P Hanlon, H Morrison, F Morton, BD Jani… - Wellcome Open …, 2022 - pmc.ncbi.nlm.nih.gov
Background: Frailty, an age-related decline in physiological reserve, is an increasingly
important concept in the management of chronic diseases. The implications of frailty in …