Extracellular vesicles as mediators of cellular crosstalk between immune system and kidney graft

M Quaglia, S Dellepiane, G Guglielmetti… - Frontiers in …, 2020 - frontiersin.org
Extracellular vesicles (EVs) are known immune-modulators exerting a critical role in kidney
transplantation (KT). EV bioactive cargo includes graft antigens, costimulatory/inhibitory …

Exosomes: emerging therapy delivery tools and biomarkers for kidney diseases

C Jin, P Wu, L Li, W Xu, H Qian - Stem cells international, 2021 - Wiley Online Library
Exosomes are nanometer‐sized small EVs coated with bilayer structure, which are released
by prokaryotic and eukaryotic cells. Exosomes are rich in a variety of biologically active …

[HTML][HTML] Mesenchymal stem cells-derived extracellular vesicles, via miR-210, improve infarcted cardiac function by promotion of angiogenesis

NA Wang, C Chen, D Yang, Q Liao, H Luo… - … et Biophysica Acta (BBA …, 2017 - Elsevier
Mesenchymal stem cells (MSCs) exert therapeutic effect on treating acute myocardial
infarction. Recent evidence showed that paracrine function rather than direct differentiation …

New insight into the role of extracellular vesicles in kidney disease

LL Lv, Y Feng, TT Tang, BC Liu - Journal of cellular and …, 2019 - Wiley Online Library
Extracellular vesicles (EVs) are released to maintain cellular homeostasis as well as to
mediate cell communication by spreading protective or injury signals to neighbour or remote …

Extracellular vesicles in renal pathophysiology

MAC Pomatto, C Gai, B Bussolati… - Frontiers in molecular …, 2017 - frontiersin.org
Extracellular vesicles are a heterogeneous population of microparticles released by virtually
all living cells which have been recently widely investigated in different biological fields …

Transfer of microRNA-216a-5p from exosomes secreted by human urine-derived stem cells reduces renal ischemia/reperfusion injury

Y Zhang, J Wang, B Yang, R Qiao, A Li… - Frontiers in cell and …, 2020 - frontiersin.org
Human urine-derived stem cells (USCs) protect rats against kidney ischemia/reperfusion
(I/R) injury. Here we investigated the role of USCs exosomes (USCs-Exos) in protecting …

Metformin promotes angiogenesis and functional recovery in aged mice after spinal cord injury by adenosine monophosphate-activated protein kinase/endothelial …

JY Zhao, XL Sheng, CJ Li, T Qin, RD He… - Neural Regeneration …, 2023 - journals.lww.com
Abstract Treatment with metformin can lead to the recovery of pleiotropic biological activities
after spinal cord injury. However, its effect on spinal cord injury in aged mice remains …

The divergent roles of exosomes in kidney diseases: pathogenesis, diagnostics, prognostics and therapeutics

V Thongboonkerd, R Kanlaya - The International Journal of Biochemistry & …, 2022 - Elsevier
Exosomes are the self-packed nanoscale vesicles (nanovesicles) derived from late
endosomes and released from the cells to the extracellular milieu. Exosomal biogenesis is …

[HTML][HTML] Potential role of exosomes in the pathophysiology, diagnosis, and treatment of hypoxic diseases

P Duan, J Tan, Y Miao, Q Zhang - American Journal of …, 2019 - ncbi.nlm.nih.gov
Exosomes are extracellular vesicles that originate in the endosomal system. They perform
important functions for cell-to-cell communication by transferring bioactive cargoes to …

Endothelial progenitor cell‐derived extracellular vesicles: a novel candidate for regenerative medicine and disease treatment

Z Xing, C Zhao, H Liu, Y Fan - Advanced healthcare materials, 2020 - Wiley Online Library
Extracellular vesicles (EVs) are a heterogeneous group of membranous structures, which
can be secreted by most cell types. As a product of paracrine secretion, EVs are considered …