A significant proportion of lesions treated with transcatheter interventions in the coronary
and peripheral vascular beds exhibit moderate to severe calcific plaques known to portend …

Atherosclerosis is a multifocal alteration of the vascular wall of medium and large arteries
characterized by a local accumulation of cholesterol and non-resolving inflammation …

Atherosclerotic plaque rupture with luminal thrombosis is the most common mechanism
responsible for the majority of acute coronary syndromes and sudden coronary death. The …

Vascular smooth muscle cells (VSMCs) are the stromal cells of the vascular wall, continually
exposed to mechanical signals and biochemical components generated in the blood …

At least 468 individual genes have been manipulated by molecular methods to study their
effects on the initiation, promotion, and progression of atherosclerosis. Most clinicians and …

Saccular intracranial aneurysms (sIA) are pouch-like pathological dilatations of intracranial
arteries that develop when the cerebral artery wall becomes too weak to resist …

Vascular inflammation is a common pathophysiological response to diverse cardiovascular
disease processes, including atherosclerosis, myocardial infarction, congestive heart failure …

An abdominal aortic aneurysm (AAA) is a localized dilatation of the infrarenal aorta. AAA is a
multifactorial disease, and genetic and environmental factors play a part; smoking, male sex …

Vascular inflammation contributes to cardiovascular diseases such as aortic aneurysm and
dissection. However, the precise inflammatory pathways involved have not been clearly …

Atherothrombosis remains one of the main causes of morbidity and mortality in the western
countries. Human atherothrombotic disease begins early in life in relation to circulating lipid …