Heart disease and stroke statistics—2022 update: a report from the American Heart Association

CW Tsao, AW Aday, ZI Almarzooq, A Alonso… - Circulation, 2022 - Am Heart Assoc
Background: The American Heart Association, in conjunction with the National Institutes of
Health, annually reports the most up-to-date statistics related to heart disease, stroke, and …

Heart disease and stroke statistics—2023 update: a report from the American Heart Association

CW Tsao, AW Aday, ZI Almarzooq, CAM Anderson… - Circulation, 2023 - Am Heart Assoc
Background: The American Heart Association, in conjunction with the National Institutes of
Health, annually reports the most up-to-date statistics related to heart disease, stroke, and …

Early-stage Alzheimer's disease prediction using machine learning models

C Kavitha, V Mani, SR Srividhya, OI Khalaf… - Frontiers in public …, 2022 - frontiersin.org
Alzheimer's disease (AD) is the leading cause of dementia in older adults. There is currently
a lot of interest in applying machine learning to find out metabolic diseases like Alzheimer's …

Alzheimer's disease prevention: from risk factors to early intervention

M Crous-Bou, C Minguillón, N Gramunt… - Alzheimer's research & …, 2017 - Springer
Due to the progressive aging of the population, Alzheimer's disease (AD) is becoming a
healthcare burden of epidemic proportions for which there is currently no cure …

Involvement of astrocytes in Alzheimer's disease from a neuroinflammatory and oxidative stress perspective

RE González-Reyes, MO Nava-Mesa… - Frontiers in molecular …, 2017 - frontiersin.org
Alzheimer disease (AD) is a frequent and devastating neurodegenerative disease in
humans, but still no curative treatment has been developed. Although many explicative …

Aging, obesity, and inflammatory age-related diseases

D Frasca, BB Blomberg, R Paganelli - Frontiers in immunology, 2017 - frontiersin.org
The increase in the prevalence of obesity represents a worldwide phenomenon in all age
groups and is pathologically and genetically correlated with several metabolic and …

Association of systolic blood pressure with dementia risk and the role of age, U-shaped associations, and mortality

JW van Dalen, C Brayne, PK Crane… - JAMA internal …, 2022 - jamanetwork.com
Importance The optimal systolic blood pressure (SBP) to minimize the risk of dementia in
older age is unknown. Objective To investigate whether the association between SBP and …

Longitudinal associations of mental disorders with dementia: 30-year analysis of 1.7 million New Zealand citizens

LS Richmond-Rakerd, S D'Souza, BJ Milne… - JAMA …, 2022 - jamanetwork.com
Importance Mental disorders are an underappreciated category of modifiable risk factors for
dementia. Developing an evidence base about the link between mental disorders and …

The role of microglia in Alzheimer's disease from the perspective of immune inflammation and iron metabolism

HZ Long, ZW Zhou, Y Cheng, HY Luo, FJ Li… - Frontiers in Aging …, 2022 - frontiersin.org
Alzheimer's disease (AD), the most common type of senile dementia, includes the complex
pathogenesis of abnormal deposition of amyloid beta-protein (Aβ), phosphorylated tau (p …

The many faces of astrocytes in Alzheimer's disease

MD Monterey, H Wei, X Wu, JQ Wu - Frontiers in Neurology, 2021 - frontiersin.org
Alzheimer's disease (AD) is a progressive neurodegenerative disease and is the most
common cause of dementia in an aging population. The majority of research effort has …