[HTML][HTML] The untapped potential of ascites in ovarian cancer research and treatment
The build-up of fluid in the peritoneal cavity—ascites—is a hallmark of ovarian cancer, the
most lethal of all gynaecological malignancies. This remarkable fluid, which contains a …
most lethal of all gynaecological malignancies. This remarkable fluid, which contains a …
[HTML][HTML] Spheroid formation and peritoneal metastasis in ovarian cancer: the role of stromal and immune components
M Rakina, A Kazakova, A Villert, L Kolomiets… - International journal of …, 2022 - mdpi.com
Ovarian cancer (OC) is one of the most common gynecological cancers, with the worst
prognosis and the highest mortality rate. Peritoneal dissemination (or carcinomatosis) …
prognosis and the highest mortality rate. Peritoneal dissemination (or carcinomatosis) …
The high-grade serous ovarian cancer metastasis and chemoresistance in 3D models
V Tadić, W Zhang, A Brozovic - … et Biophysica Acta (BBA)-Reviews on …, 2023 - Elsevier
High-grade serous ovarian cancer (HGSOC) is the most frequent and aggressive type of
epithelial ovarian cancer, with high recurrence rate and chemoresistance being the main …
epithelial ovarian cancer, with high recurrence rate and chemoresistance being the main …
[HTML][HTML] Metabolic Priming as a Tool in Redox and Mitochondrial Theragnostics
SA Pinho, SI Anjo, T Cunha-Oliveira - Antioxidants, 2023 - mdpi.com
Theragnostics is a promising approach that integrates diagnostics and therapeutics into a
single personalized strategy. To conduct effective theragnostic studies, it is essential to …
single personalized strategy. To conduct effective theragnostic studies, it is essential to …
[HTML][HTML] Gene expression in organoids: an expanding horizon
Recent development of human three-dimensional organoid cultures has opened new doors
and opportunities ranging from modelling human development in vitro to personalised …
and opportunities ranging from modelling human development in vitro to personalised …
[HTML][HTML] In vitro models of ovarian cancer: bridging the gap between pathophysiology and mechanistic models
Ovarian cancer (OC) is a disease of major concern with a survival rate of about 40% at five
years. This is attributed to the lack of visible and reliable symptoms during the onset of the …
years. This is attributed to the lack of visible and reliable symptoms during the onset of the …
Chemoresistance in ovarian cancer: the role of Malignant ascites
M Nunes, S Ricardo - Exon Publications, 2022 - exonpublications.com
Ascites is an inflammatory process that induces the abnormal accumulation of a large
amount of fluid into the peritoneal cavity. This pathological condition is observed in many …
amount of fluid into the peritoneal cavity. This pathological condition is observed in many …
[HTML][HTML] 3D tumor spheroid and organoid to model tumor microenvironment for cancer immunotherapy
The intricate microenvironment in which malignant cells reside is essential for the
progression of tumor growth. Both the physical and biochemical features of the tumor …
progression of tumor growth. Both the physical and biochemical features of the tumor …
[HTML][HTML] Polyploidy, EZH2 upregulation, and transformation in cytomegalovirus-infected human ovarian epithelial cells
R El Baba, S Haidar Ahmad, F Monnien, R Mansar… - Oncogene, 2023 - nature.com
Human cytomegalovirus (HCMV) infection has been implicated in epithelial ovarian cancer
(OC). Polyploidy giant cancer cells (PGCCs) have been observed in high-grade serous …
(OC). Polyploidy giant cancer cells (PGCCs) have been observed in high-grade serous …
Multifaceted Cancer Alleviation by Cowpea Mosaic Virus in a Bioprinted Ovarian Cancer Peritoneal Spheroid Model
Ovarian cancer (OvCa) is a leading cause of mortality among gynecological malignancies
and usually manifests as intraperitoneal spheroids that generate metastases, ascites, and …
and usually manifests as intraperitoneal spheroids that generate metastases, ascites, and …