Colorectal cancer (CRC) is one of the most common types of cancer in the world. Several
factors contribute to the development of this cancer. Tumor formation in colon triggers …

Although immune checkpoint inhibitors (ICIs) have gained much attention in managing
cancer, only a minority of patients, especially those with tumors that have been classified as …

BACKGROUND & AIMS: Although the Milan criteria (MC) have been used to select liver
transplantation candidates among patients with hepatocellular carcinoma (HCC), many …

Background It has been previously reported that IL-22, one of the cytokines secreted by
Th17 cells, demonstrates both a protective and inflammatory promotion effect in …

It is widely accepted that chronic inflammation plays an active role in cancer. Inflammatory
immunocytes and related cytokines in the tumor microenvironment are supposed to be a …

BACKGROUND The connection between inflammatory bowel disease (IBD) and colorectal
cancer (CRC) is well-established, as persistent intestinal inflammation plays a substantial …

Cancer is the primary cause of death in economically developed countries and the second
leading cause in developing countries. Colorectal cancer (CRC) is the third most common …

The development of colorectal cancer (CRC) is not only determined by transformed cells per
se, but also by factors existing in their immune microenvironment. Accumulating scientific …

Colorectal cancer is a major problem for public health worldwide because of its frequency
and its severity. Many efforts have been carried to target the vascular endothelial growth …

Background IL-17 family of cytokines and human IL-23R play important and sometimes
contradictory roles in autoimmune and inflammatory diseases as well as human …