CRISPR/Cas9 Protocols for Disrupting Gene Function in the Non-vertebrate Chordate Ciona

S Popsuj, L Cohen, S Ward, A Lewis… - Integrative and …, 2024 - academic.oup.com
The evolutionary origins of chordates and their diversification into the three major subphyla
of tunicates, vertebrates, and cephalochordates pose myriad questions about the genetic …

Cardiopharyngeal progenitor specification: multiple roads to the heart and head muscles

B Swedlund, F Lescroart - Cold Spring Harbor …, 2020 - cshperspectives.cshlp.org
During embryonic development, the heart arises from various sources of undifferentiated
mesodermal progenitors, with an additional contribution from ectodermal neural crest cells …

Improved Genome Editing in the Ascidian Ciona with CRISPR/Cas9 and TALEN

Y Sasakura, T Horie - Genome Editing in Animals: Methods and Protocols, 2023 - Springer
The ascidian Ciona intestinalis type A (or Ciona robusta) is an important organism for
elucidating the mechanisms that make the chordate body plan. CRISPR/Cas9 and TAL …

LncRNA4930473A02Rik promotes cardiac hypertrophy by regulating TCF7 via sponging miR-135a in mice

J Ren, H Qi, C Song, L Ba, R Liu, X Feng, L Wang… - Cell Death …, 2021 - nature.com
Cardiac hypertrophy is a common pathological change accompanied by various
cardiovascular diseases; however, its underlying mechanisms remain elusive. Mounting …

[HTML][HTML] Conserved Signaling Pathways in the Ciona robusta Gut

M Gerdol, S Greco, R Marino, A Locascio… - International Journal of …, 2024 - mdpi.com
The urochordate Ciona robusta exhibits numerous functional and morphogenetic traits that
are shared with vertebrate models. While prior investigations have identified several …

Quantitative proteome dynamics across embryogenesis in a model chordate

AN Frese, A Mariossi, MS Levine, M Wühr - Iscience, 2024 - cell.com
The evolution of gene expression programs underlying the development of vertebrates
remains poorly characterized. Here, we present a comprehensive proteome atlas of the …

Exploration of the regulatory mechanisms of regeneration, anti-oxidation, anti-aging and the immune response at the post-molt stage of Eriocheir sinensis

M Wang, J Ge, X Ma, S Su, C Tian, J Li, F Yu… - Frontiers in …, 2022 - frontiersin.org
Eriocheir sinensis is widely appreciated by the surrounding population due to its culinary
delicacy and rich nutrients. The E. sinensis breeding industry is very prosperous and molting …

CRISPR-Cas9 como herramienta para describir la función genética en metazoarios marinos

SY Morán Garay, L Rojo Arreola - Revista de biología marina y …, 2022 - SciELO Chile
Las herramientas de edición genética han transformado la manera en que se estudia la
función de los genes y proteínas de los sistemas biológicos. Especialmente CRISPR-Cas9 …

[PDF][PDF] Cell Fate Choices and Developmental Competence in the Avian Head Mesoderm

AMAM Alzamrooni - 2023 - researchportal.port.ac.uk
CELL FATE CHOICES AND DEVELOPMENTAL COMPETENCE IN THE AVIAN HEAD
MESODERM Page 1 UNIVERSITY of PORTSMOUTH CELL FATE CHOICES AND …

CRISPR-Cas9 como herramienta para describir la función genética en metazoarios marinos

SYM Garay, LR Arreola - Revista de biología marina y …, 2022 - dialnet.unirioja.es
Las herramientas de edición genética han transformado la manera en que se estudia la
función de los genes y proteínas de los sistemas biológicos. Especialmente CRISPR-Cas9 …