The immunological and metabolic landscape in primary and metastatic liver cancer
X Li, P Ramadori, D Pfister, M Seehawer… - Nature Reviews …, 2021 - nature.com
The liver is the sixth most common site of primary cancer in humans, and generally arises in
a background of cirrhosis and inflammation. Moreover, the liver is frequently colonized by …
a background of cirrhosis and inflammation. Moreover, the liver is frequently colonized by …
CD44 as a tumor biomarker and therapeutic target
H Xu, M Niu, X Yuan, K Wu, A Liu - Experimental hematology & oncology, 2020 - Springer
CD44, a complex transmembrane glycoprotein, exists in multiple molecular forms, including
the standard isoform CD44s and CD44 variant isoforms. CD44 participates in multiple …
the standard isoform CD44s and CD44 variant isoforms. CD44 participates in multiple …
Opposing roles of hepatic stellate cell subpopulations in hepatocarcinogenesis
Hepatocellular carcinoma (HCC), the fourth leading cause of cancer mortality worldwide,
develops almost exclusively in patients with chronic liver disease and advanced fibrosis …
develops almost exclusively in patients with chronic liver disease and advanced fibrosis …
Characterizing dedifferentiation of thyroid cancer by integrated analysis
Understanding of dedifferentiation, an indicator of poo prognosis for patients with thyroid
cancer, has been hampered by imprecise and incomplete characterization of its …
cancer, has been hampered by imprecise and incomplete characterization of its …
Cancer stem cell functions in hepatocellular carcinoma and comprehensive therapeutic strategies
YC Liu, CT Yeh, KH Lin - Cells, 2020 - mdpi.com
Hepatocellular carcinoma (HCC) is a significant cause of cancer-related mortality owing to
resistance to traditional treatments and tumor recurrence after therapy, which leads to poor …
resistance to traditional treatments and tumor recurrence after therapy, which leads to poor …
Long noncoding RNA LINC00662 promotes M2 macrophage polarization and hepatocellular carcinoma progression via activating Wnt/β‐catenin signaling
X Tian, Y Wu, Y Yang, J Wang, M Niu, S Gao… - Molecular …, 2020 - Wiley Online Library
Tumor‐associated macrophages have important roles in hepatocellular carcinoma (HCC)
initiation and progression. Long noncoding RNAs (lncRNAs) have also been reported to be …
initiation and progression. Long noncoding RNAs (lncRNAs) have also been reported to be …
The cancer-testis lncRNA lnc-CTHCC promotes hepatocellular carcinogenesis by binding hnRNP K and activating YAP1 transcription
A Xia, W Yuan, Q Wang, J Xu, Y Gu, L Zhang, C Chen… - Nature cancer, 2022 - nature.com
Cancer-testis (CT) genes participate in the initiation and progression of cancer, but the role
of CT-associated long non-coding RNAs (CT-lncRNAs) in hepatocellular carcinoma (HCC) …
of CT-associated long non-coding RNAs (CT-lncRNAs) in hepatocellular carcinoma (HCC) …
m6A RNA methylation-mediated HNF3γ reduction renders hepatocellular carcinoma dedifferentiation and sorafenib resistance
T Zhou, S Li, D Xiang, J Liu, W Sun, X Cui… - Signal transduction and …, 2020 - nature.com
Hepatocyte nuclear factor 3γ (HNF3γ) is a hepatocyte nuclear factor, but its role and clinical
significance in hepatocellular carcinoma (HCC) remain unclear. Herein, we report that …
significance in hepatocellular carcinoma (HCC) remain unclear. Herein, we report that …
Hyaluronic acid as a modern approach in anticancer therapy-review
M Michalczyk, E Humeniuk, G Adamczuk… - International Journal of …, 2022 - mdpi.com
Hyaluronic acid (HA) is a linear polysaccharide and crucial component of the extracellular
matrix (ECM), maintaining tissue hydration and tension. Moreover, HA contributes to …
matrix (ECM), maintaining tissue hydration and tension. Moreover, HA contributes to …
Molecular bases of drug resistance in hepatocellular carcinoma
The poor outcome of patients with non-surgically removable advanced hepatocellular
carcinoma (HCC), the most frequent type of primary liver cancer, is mainly due to the high …
carcinoma (HCC), the most frequent type of primary liver cancer, is mainly due to the high …