Hepatic macrophages in homeostasis and liver diseases: from pathogenesis to novel therapeutic strategies
C Ju, F Tacke - Cellular & molecular immunology, 2016 - nature.com
Macrophages represent a major cell type of innate immunity and have emerged as a critical
player and therapeutic target in many chronic inflammatory diseases. Hepatic macrophages …
player and therapeutic target in many chronic inflammatory diseases. Hepatic macrophages …
NAFLD and liver transplantation: current burden and expected challenges
Because of global epidemics of obesity and type 2 diabetes, the prevalence of non-alcoholic
fatty liver disease (NAFLD) is increasing both in Europe and the United States, becoming …
fatty liver disease (NAFLD) is increasing both in Europe and the United States, becoming …
Precision navigation of hepatic ischemia–reperfusion injury guided by lysosomal viscosity-activatable NIR-II fluorescence
J Liu, W Zhang, C Zhou, M Li, X Wang… - Journal of the …, 2022 - ACS Publications
Hepatic ischemia–reperfusion injury (HIRI) is responsible for postoperative liver dysfunction
and liver failure. Precise and rapid navigation of HIRI lesions is critical for early warning and …
and liver failure. Precise and rapid navigation of HIRI lesions is critical for early warning and …
AH2O2-activatable nanoprobe for diagnosing interstitial cystitis and liver ischemia-reperfusion injury via multispectral optoacoustic tomography and NIR-II …
J Chen, L Chen, Y Wu, Y Fang, F Zeng, S Wu… - Nature …, 2021 - nature.com
Developing high-quality NIR-II fluorophores (emission in 1000–1700 nm) for in vivo imaging
is of great significance. Benzothiadiazole-core fluorophores are an important class of NIR-II …
is of great significance. Benzothiadiazole-core fluorophores are an important class of NIR-II …
Inflammasome activation and function in liver disease
G Szabo, J Petrasek - Nature reviews Gastroenterology & hepatology, 2015 - nature.com
Inflammation contributes to the pathogenesis of most acute and chronic liver diseases.
Inflammasomes are multiprotein complexes that can sense danger signals from damaged …
Inflammasomes are multiprotein complexes that can sense danger signals from damaged …
Ischaemia–reperfusion injury in liver transplantation—from bench to bedside
Y Zhai, H Petrowsky, JC Hong, RW Busuttil… - Nature reviews …, 2013 - nature.com
Ischaemia–reperfusion injury (IRI) in the liver, a major complication of haemorrhagic shock,
resection and transplantation, is a dynamic process that involves the two interrelated phases …
resection and transplantation, is a dynamic process that involves the two interrelated phases …
[HTML][HTML] Hepatic ischemia reperfusion injury: A systematic review of literature and the role of current drugs and biomarkers
M Cannistrà, M Ruggiero, A Zullo, G Gallelli… - International journal of …, 2016 - Elsevier
Hepatic ischemia reperfusion injury (IRI) is not only a pathophysiological process involving
the liver, but also a complex systemic process affecting multiple tissues and organs. Hepatic …
the liver, but also a complex systemic process affecting multiple tissues and organs. Hepatic …
The immunological basis of liver allograft rejection
Liver allograft rejection remains a significant cause of morbidity and graft failure in liver
transplant recipients. Rejection is caused by the recognition of non-self donor alloantigens …
transplant recipients. Rejection is caused by the recognition of non-self donor alloantigens …
[HTML][HTML] Apoptosis and necrosis in the liver
ME Guicciardi, H Malhi, JL Mott… - Comprehensive …, 2013 - ncbi.nlm.nih.gov
Because of its unique function and anatomical location, the liver is exposed to a multitude of
toxins and xenobiotics, including medications and alcohol, as well as to infection by …
toxins and xenobiotics, including medications and alcohol, as well as to infection by …