Macrophages represent a major cell type of innate immunity and have emerged as a critical
player and therapeutic target in many chronic inflammatory diseases. Hepatic macrophages …

Because of global epidemics of obesity and type 2 diabetes, the prevalence of non-alcoholic
fatty liver disease (NAFLD) is increasing both in Europe and the United States, becoming …

Hepatic ischemia–reperfusion injury (HIRI) is responsible for postoperative liver dysfunction
and liver failure. Precise and rapid navigation of HIRI lesions is critical for early warning and …

Developing high-quality NIR-II fluorophores (emission in 1000–1700 nm) for in vivo imaging
is of great significance. Benzothiadiazole-core fluorophores are an important class of NIR-II …

Inflammation contributes to the pathogenesis of most acute and chronic liver diseases.
Inflammasomes are multiprotein complexes that can sense danger signals from damaged …

Ischaemia–reperfusion injury (IRI) in the liver, a major complication of haemorrhagic shock,
resection and transplantation, is a dynamic process that involves the two interrelated phases …

Hepatic ischemia reperfusion injury (IRI) is not only a pathophysiological process involving
the liver, but also a complex systemic process affecting multiple tissues and organs. Hepatic …

Inflammation In the absence of pathogens occurs in all tissues in response to a wide range
of stimuli that cause tissue stress and injury. Such sterile inflammation (SI) is a key process …

Liver allograft rejection remains a significant cause of morbidity and graft failure in liver
transplant recipients. Rejection is caused by the recognition of non-self donor alloantigens …

Because of its unique function and anatomical location, the liver is exposed to a multitude of
toxins and xenobiotics, including medications and alcohol, as well as to infection by …