Adverse outcome pathways for ionizing radiation and breast cancer involve direct and indirect DNA damage, oxidative stress, inflammation, genomic instability, and …
JS Helm, RA Rudel - Archives of toxicology, 2020 - Springer
Abstract Knowledge about established breast carcinogens can support improved and
modernized toxicological testing methods by identifying key mechanistic events. Ionizing …
modernized toxicological testing methods by identifying key mechanistic events. Ionizing …
The potential preventive and therapeutic roles of NSAIDs in prostate cancer
H Maghsoudi, F Sheikhnia, P Sitarek, N Hajmalek… - Cancers, 2023 - mdpi.com
Simple Summary Prostate cancer is a serious health problem for men around the world, and
it is often caused by inflammation in the prostate gland. The authors of this article explore …
it is often caused by inflammation in the prostate gland. The authors of this article explore …
Small molecule therapeutics for COVID-19: repurposing of inhaled furosemide
The novel coronavirus SARS-CoV-2 has become a global health concern. The morbidity
and mortality of the potentially lethal infection caused by this virus arise from the initial viral …
and mortality of the potentially lethal infection caused by this virus arise from the initial viral …
Niosomal formulation of mefenamic acid for enhanced cancer targeting; preparation, characterization and biodistribution study using radiolabeling technique
Background This work aimed to prepare niosomal formulations of an anticancer agent
[mefenamic acid (MEF)] to enhance its cancer targeting. 131I was utilized as a radiolabeling …
[mefenamic acid (MEF)] to enhance its cancer targeting. 131I was utilized as a radiolabeling …
Radioprotective effect of cerium oxide nanoparticles against genotoxicity induced by ionizing radiation on human lymphocytes
Z Zal, A Ghasemi, S Azizi… - Current …, 2018 - ingentaconnect.com
Background: Ionizing radiation induces DNA damage on normal cell results in apoptosis
and cell deaths. Objectives: The radioprotective effects of cerium oxide nanoparticles …
and cell deaths. Objectives: The radioprotective effects of cerium oxide nanoparticles …
Mefenamic acid as a promising therapeutic medicine against colon cancer in tumor-bearing mice
R Seyyedi, F Talebpour Amiri, S Farzipour… - Medical Oncology, 2022 - Springer
Although radiotherapy is an effective strategy for cancer treatment, tumor resistance to
ionizing radiation (IR) and its toxic effects on normal tissues are limiting its use. The aim of …
ionizing radiation (IR) and its toxic effects on normal tissues are limiting its use. The aim of …
Radioprotective effect of gliclazide as an anti-hyperglycemic agent against genotoxicity induced by ionizing radiation on human lymphocytes
M Pouri, Z Shaghaghi, A Ghasemi… - … Agents in Medicinal …, 2019 - ingentaconnect.com
Objectives: Gliclazide (GL) is widely used to reduce hyperglycemia in diabetic patients. The
aim of this study was to investigate the protective effect of GL against chromosome damage …
aim of this study was to investigate the protective effect of GL against chromosome damage …
Celecoxib mitigates genotoxicity induced by ionizing radiation in human blood lymphocytes
SJ Hosseinimehr, M Fathi, A Ghasemi… - Research in …, 2017 - journals.lww.com
Ionizing radiation causes DNA damage and chromosome abbreviations on normal cells.
The radioprotective effect of celecoxib (CLX) was investigated against genotoxicity induced …
The radioprotective effect of celecoxib (CLX) was investigated against genotoxicity induced …
Radioprotective effect of diethylcarbamazine on radiation-induced acute lung injury and oxidative stress in mice
S Farzipour, FT Amiri, E Mihandoust, F Shaki… - Journal of bioenergetics …, 2020 - Springer
The present study was designed to evaluate the radioprotective effect of diethylcarbamazine
(DEC) against oxidative stress and acute lung injury induced by total body radiation (TBI) in …
(DEC) against oxidative stress and acute lung injury induced by total body radiation (TBI) in …
The synergistic effect of mefenamic acid with ionizing radiation in colon cancer
SJ Hosseinimehr, Z Safavi… - Journal of Bioenergetics …, 2019 - Springer
Despite radiotherapy is an effective regimen in cancer treatment, resistance to tumor therapy
still is a major challenge to radiotherapy and results in cancer recurrence and metastasis …
still is a major challenge to radiotherapy and results in cancer recurrence and metastasis …