[HTML][HTML] Mechanisms of SARS-CoV-2 entry into cells
The unprecedented public health and economic impact of the COVID-19 pandemic caused
by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been …
by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been …
Immune determinants of COVID-19 disease presentation and severity
P Brodin - Nature medicine, 2021 - nature.com
Abstract COVID-19, caused by SARS-CoV-2 infection, is mild to moderate in the majority of
previously healthy individuals, but can cause life-threatening disease or persistent …
previously healthy individuals, but can cause life-threatening disease or persistent …
Mechanisms of SARS-CoV-2 transmission and pathogenesis
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) marks
the third highly pathogenic coronavirus to spill over into the human population. SARS-CoV-2 …
the third highly pathogenic coronavirus to spill over into the human population. SARS-CoV-2 …
ACE2: the major cell entry receptor for SARS-CoV-2
Despite the unprecedented effort of the scientific community, the novel SARS-CoV-2 virus
has infected more than 46 million people worldwide, killing over one million two hundred …
has infected more than 46 million people worldwide, killing over one million two hundred …
Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics
Abstract Angiotensin-converting enzyme 2 (ACE2) and accessory proteases (TMPRSS2 and
CTSL) are needed for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …
CTSL) are needed for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …
Clinical impact of COVID-19 on patients with cancer (CCC19): a cohort study
Background Data on patients with COVID-19 who have cancer are lacking. Here we
characterise the outcomes of a cohort of patients with cancer and COVID-19 and identify …
characterise the outcomes of a cohort of patients with cancer and COVID-19 and identify …
Genome-wide CRISPR screens reveal host factors critical for SARS-CoV-2 infection
Identification of host genes essential for severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) infection may reveal novel therapeutic targets and inform our understanding …
(SARS-CoV-2) infection may reveal novel therapeutic targets and inform our understanding …
[HTML][HTML] Why does COVID-19 disproportionately affect older people?
AL Mueller, MS McNamara, DA Sinclair - Aging (albany NY), 2020 - ncbi.nlm.nih.gov
The severity and outcome of coronavirus disease 2019 (COVID-19) largely depends on a
patient's age. Adults over 65 years of age represent 80% of hospitalizations and have a 23 …
patient's age. Adults over 65 years of age represent 80% of hospitalizations and have a 23 …
The effect of smoking on COVID‐19 severity: A systematic review and meta‐analysis
RK Reddy, WN Charles, A Sklavounos… - Journal of medical …, 2021 - Wiley Online Library
Various comorbidities represent risk factors for severe coronavirus disease 2019 (COVID‐
19). The impact of smoking on COVID‐19 severity has been previously reported in several …
19). The impact of smoking on COVID‐19 severity has been previously reported in several …
Mental health and clinical psychological science in the time of COVID-19: Challenges, opportunities, and a call to action.
COVID-19 presents significant social, economic, and medical challenges. Because COVID-
19 has already begun to precipitate huge increases in mental health problems, clinical …
19 has already begun to precipitate huge increases in mental health problems, clinical …