Greasing the wheels of the cancer machine: the role of lipid metabolism in cancer

MT Snaebjornsson, S Janaki-Raman, A Schulze - Cell metabolism, 2020 - cell.com
Altered lipid metabolism is among the most prominent metabolic alterations in cancer.
Enhanced synthesis or uptake of lipids contributes to rapid cancer cell growth and tumor …

A review on anti-cancer properties of Quercetin in breast cancer

M Ezzati, B Yousefi, K Velaei, A Safa - Life sciences, 2020 - Elsevier
Breast cancer is one of the well-known malignant tumors among women. In spite of attempts
to classifying breast cancer according to its histological and molecular properties, it is almost …

Lipid desaturation is a metabolic marker and therapeutic target of ovarian cancer stem cells

J Li, S Condello, J Thomes-Pepin, X Ma, Y Xia… - Cell stem cell, 2017 - cell.com
Lack of sensitive single-cell analysis tools has limited the characterization of metabolic
activity in cancer stem cells. By hyperspectral-stimulated Raman scattering imaging of single …

Hallmarks of cancer stem cell metabolism

P Sancho, D Barneda, C Heeschen - British journal of cancer, 2016 - nature.com
Cancer cells adapt cellular metabolism to cope with their high proliferation rate. Instead of
primarily using oxidative phosphorylation (OXPHOS), cancer cells use less efficient …

Targeting cancer stem cells and signaling pathways by phytochemicals: Novel approach for breast cancer therapy

PR Dandawate, D Subramaniam, RA Jensen… - Seminars in cancer …, 2016 - Elsevier
Breast cancer is the most common form of cancer diagnosed in women worldwide and the
second leading cause of cancer-related deaths in the USA. Despite the development of …

Cancer stem cells (CSCs): metabolic strategies for their identification and eradication

EM De Francesco, F Sotgia, MP Lisanti - Biochemical Journal, 2018 - portlandpress.com
Phenotypic and functional heterogeneity is one of the most relevant features of cancer cells
within different tumor types and is responsible for treatment failure. Cancer stem cells …

Fatty acid synthase (FASN) as a therapeutic target in breast cancer

JA Menendez, R Lupu - Expert opinion on therapeutic targets, 2017 - Taylor & Francis
Introduction: Ten years ago, we put forward the metabolo-oncogenic nature of fatty acid
synthase (FASN) in breast cancer. Since the conception of this hypothesis, which provided a …

Resveratrol‐loaded nanomedicines for cancer applications

M Annaji, I Poudel, SHS Boddu, RD Arnold… - Cancer …, 2021 - Wiley Online Library
Abstract Background Resveratrol (3, 5, 4′‐trihydroxystilbene), a natural polyphenol and
phytoalexin, has drawn considerable attention in the past decade due to its wide variety of …

Emerging role of lipid metabolism alterations in Cancer stem cells

M Yi, J Li, S Chen, J Cai, Y Ban, Q Peng, Y Zhou… - Journal of Experimental …, 2018 - Springer
Abstract Background Cancer stem cells (CSCs) or tumor-initiating cells (TICs) represent a
small population of cancer cells with self-renewal and tumor-initiating properties. Unlike the …

Stability and solubility of trans-resveratrol are strongly influenced by pH and temperature

Š Zupančič, Z Lavrič, J Kristl - European Journal of Pharmaceutics and …, 2015 - Elsevier
Recently trans-resveratrol (trans-RSV) has received great attention due to its prophylactic
and therapeutic properties. Its limited bioavailability provides compelling evidence of the …