Neurofilament light chain in blood as a diagnostic and predictive biomarker for multiple sclerosis: A systematic review and meta-analysis
L Ning, B Wang - PLoS One, 2022 - journals.plos.org
Background Neurofilament light chain (NfL) in cerebrospinal fluid (CSF) is a biomarker of
multiple sclerosis (MS). However, CSF sampling is invasive and has limited the clinical …
multiple sclerosis (MS). However, CSF sampling is invasive and has limited the clinical …
[HTML][HTML] Guidance for use of neurofilament light chain as a cerebrospinal fluid and blood biomarker in multiple sclerosis management
MS Freedman, S Gnanapavan, RA Booth… - …, 2024 - thelancet.com
Neurofilament light chain (NfL) is a long-awaited blood biomarker that can provide clinically
useful information about prognosis and therapeutic efficacy in multiple sclerosis (MS). There …
useful information about prognosis and therapeutic efficacy in multiple sclerosis (MS). There …
Contributors to serum NfL levels in people without neurologic disease
Objective To assess the effects of demographics, lifestyle factors, and comorbidities on
serum neurofilament light chain (sNfL) levels in people without neurologic disease and …
serum neurofilament light chain (sNfL) levels in people without neurologic disease and …
Glial fibrillary acidic protein as a biomarker in neuromyelitis optica spectrum disorder: a current review
P Schindler, O Aktas, M Ringelstein… - Expert Review of …, 2023 - Taylor & Francis
Introduction Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing, often
debilitating neuroinflammatory disease, whose predominant clinical manifestations are …
debilitating neuroinflammatory disease, whose predominant clinical manifestations are …
Validity of serum neurofilament light chain as a prognostic biomarker of disease activity in multiple sclerosis
Multiple sclerosis (MS) is a chronic demyelinating and neuroinflammatory disease of the
human central nervous system with complex pathoetiology, heterogeneous presentations …
human central nervous system with complex pathoetiology, heterogeneous presentations …
Serum neurofilament light chain levels at attack predict post-attack disability worsening and are mitigated by inebilizumab: analysis of four potential biomarkers in …
O Aktas, HP Hartung, MA Smith, WA Rees… - Journal of Neurology …, 2023 - jnnp.bmj.com
Objective To investigate relationships between serum neurofilament light chain (sNfL),
ubiquitin C-terminal hydrolase L1 (sUCHL1), tau (sTau) and glial fibrillary acidic protein …
ubiquitin C-terminal hydrolase L1 (sUCHL1), tau (sTau) and glial fibrillary acidic protein …
Serum neurofilament light chain concentration predicts disease worsening in multiple sclerosis
S Brune, EA Høgestøl… - Multiple Sclerosis …, 2022 - journals.sagepub.com
Background: Serum neurofilament light (sNfL) chain is a promising biomarker reflecting
neuro-axonal injury in multiple sclerosis (MS). However, the ability of sNfL to predict …
neuro-axonal injury in multiple sclerosis (MS). However, the ability of sNfL to predict …
Fluid biomarkers in multiple sclerosis: from current to future applications
M Di Filippo, L Gaetani, D Centonze… - The Lancet Regional …, 2024 - thelancet.com
Multiple sclerosis (MS) is an immune-mediated inflammatory and degenerative disorder of
the central nervous system (CNS) with heterogeneous clinical manifestations. In the last …
the central nervous system (CNS) with heterogeneous clinical manifestations. In the last …
Recommendations for the diagnosis and treatment of multiple sclerosis relapses
C Ramo-Tello, Y Blanco, L Brieva, B Casanova… - Journal of Personalized …, 2021 - mdpi.com
Minimizing the risk of relapse is essential in multiple sclerosis (MS). As none of the
treatments currently available are capable of completely preventing relapses, treatment of …
treatments currently available are capable of completely preventing relapses, treatment of …
Association of the retinal vasculature, intrathecal immunity, and disability in multiple sclerosis
C Noll, M Hiltensperger, L Aly, R Wicklein… - Frontiers in …, 2022 - frontiersin.org
Background Optical coherence tomography angiography (OCT-A) is a novel technique
allowing non-invasive assessment of the retinal vasculature. During relapsing remitting …
allowing non-invasive assessment of the retinal vasculature. During relapsing remitting …