Synthetic oligonucleotide analogs have greatly aided our understanding of several
biochemical processes. Efficient solid-phase and enzyme-assisted synthetic methods and …

Modification of the heterocyclic moiety of oligonucleotides has led to the discovery of potent
antisense compounds. This review describes the physicochemical factors that are …

RNA labeling is crucial for the study of RNA structure and metabolism. Herein we report N 6-
allyladenosine (a6A) as a new small molecule for RNA labeling through both metabolic and …

In this review we describe the influence of modified nucleobases in order to understand the
changes they introduce in double and triple helix forming oligomers with the aim to study …

Zusammenfassung Tempo, TEMPO! Spin-labeled RNAs are readily prepared by
postsynthetic modification of RNA. This approach provides access to paramagnetic …

The chemical synthesis of modified oligoribonucleotides represents a powerful approach to
study the structure, stability, and biological activity of RNAs. Selected RNA modifications …

Methods for RNA functionalization at specific sites are in high demand but remain a
challenge, particularly for RNAs produced by transcription rather than by total synthesis …

Chemically stable nitroxide radicals that can be monitored by electron paramagnetic
resonance (EPR) spectroscopy can provide information on structural and dynamic …

ADARs are a denosine dea minases that act on R NA and are responsible for RNA-editing
reactions that occur in eukaryotic mRNAs, including the mRNAs of glutamate and serotonin …

RNA-sequencing (RNA-seq) measures RNA abundance in a biological sample but does not
provide temporal information about the sequenced RNAs. Metabolic labeling can be used to …