Development and evolution of the human neocortex
The size and surface area of the mammalian brain are thought to be critical determinants of
intellectual ability. Recent studies show that development of the gyrated human neocortex …
intellectual ability. Recent studies show that development of the gyrated human neocortex …
Cortical progenitor expansion, self-renewal and neurogenesis—a polarized perspective
SA Fietz, WB Huttner - Current opinion in neurobiology, 2011 - Elsevier
Neural stem and progenitor cells giving rise to neurons in developing mammalian neocortex
fall into two principal classes with regard to location of mitosis—apical and basal, and into …
fall into two principal classes with regard to location of mitosis—apical and basal, and into …
Crosstalk between small-cell lung cancer cells and astrocytes mimics brain development to promote brain metastasis
Brain metastases represent an important clinical problem for patients with small-cell lung
cancer (SCLC). However, the mechanisms underlying SCLC growth in the brain remain …
cancer (SCLC). However, the mechanisms underlying SCLC growth in the brain remain …
D-cysteine is an endogenous regulator of neural progenitor cell dynamics in the mammalian brain
ER Semenza, MM Harraz… - Proceedings of the …, 2021 - National Acad Sciences
d-amino acids are increasingly recognized as important signaling molecules in the
mammalian central nervous system. However, the d-stereoisomer of the amino acid with the …
mammalian central nervous system. However, the d-stereoisomer of the amino acid with the …
MARCKS and MARCKS-like proteins in development and regeneration
Abstract Background The Myristoylated Alanine-Rich C-kinase Substrate (MARCKS) and
MARCKS-like protein 1 (MARCKSL1) have a wide range of functions, ranging from roles in …
MARCKS-like protein 1 (MARCKSL1) have a wide range of functions, ranging from roles in …
The physiological role of the amyloid precursor protein as an adhesion molecule in the developing nervous system
The amyloid precursor protein (APP) is a type I transmembrane glycoprotein better known
for its participation in the physiopathology of Alzheimer disease as the source of the beta …
for its participation in the physiopathology of Alzheimer disease as the source of the beta …
The role of Rho GTPase proteins in CNS neuronal migration
EE Govek, ME Hatten… - Developmental …, 2011 - Wiley Online Library
The architectonics of the mammalian brain arise from a remarkable range of directed cell
migrations, which orchestrate the emergence of cortical neuronal layers and pattern brain …
migrations, which orchestrate the emergence of cortical neuronal layers and pattern brain …
Mutations in Eml1 lead to ectopic progenitors and neuronal heterotopia in mouse and human
M Kielar, FPD Tuy, S Bizzotto, C Lebrand… - Nature …, 2014 - nature.com
Neuronal migration disorders such as lissencephaly and subcortical band heterotopia are
associated with epilepsy and intellectual disability. DCX, PAFAH1B1 and TUBA1A are …
associated with epilepsy and intellectual disability. DCX, PAFAH1B1 and TUBA1A are …
Polymicrogyria: pathology, fetal origins and mechanisms
W Squier, A Jansen - Acta neuropathologica communications, 2014 - Springer
Polymicrogyria (PMG) is a complex cortical malformation which has so far defied any
mechanistic or genetic explanation. Adopting a broad definition of an abnormally folded or …
mechanistic or genetic explanation. Adopting a broad definition of an abnormally folded or …
Coordinating cerebral cortical construction and connectivity: Unifying influence of radial progenitors
CR Casingal, KD Descant, ES Anton - Neuron, 2022 - cell.com
Radial progenitor development and function lay the foundation for the construction of the
cerebral cortex. Radial glial scaffold, through its functions as a source of neurogenic …
cerebral cortex. Radial glial scaffold, through its functions as a source of neurogenic …